×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Clinical Variant Classification: A Comparison of Public Databases and a Commercial Testing Laboratory.
28408614
2017
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Spectrum of genetic variants of BRCA1 and BRCA2 in a German single center study.
28324225
2017
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Pathologic characteristics of breast parenchyma in patients with hereditary breast carcinoma, including BRCA1 and BRCA2 mutation carriers.
12491499
2003
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
The prevalence of BRCA1 and BRCA2 germline mutations in high-risk breast cancer patients of Chinese Han nationality: two recurrent mutations were identified.
17851763
2008
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Racial differences in the incidence of BRCA1 and BRCA2 mutations in a cohort of early onset breast cancer patients: African American compared to white women.
15983021
2006
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Marker segregation information in breast/ovarian cancer genetic counseling: is it still useful? Groupe Génétique et Cancer de la Fédération Nationale des Centres de Lutte Contre le Cancer.
9788557
1998
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer.
15133502
2004
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Breast cancer genetics in African Americans.
12491487
2003
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition.
15385441
2004
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.
17308087
2007
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Thermal unfolding of human BRCA1 BRCT-domain variants.
17493881
2007
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Missense mutations in the BRCT domain of BRCA-1 from high-risk women frequently perturb strongly hydrophobic amino acids conserved among mammals.
15184261
2004
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias (Northern Spain).
23683081
2013
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Intronic variants in BRCA1 and BRCA2 that affect RNA splicing can be reliably selected by splice-site prediction programs.
18693280
2009
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Flexible, scalable, and efficient targeted resequencing on a benchtop sequencer for variant detection in clinical practice.
25504618
2015
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
One in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations: results of a prospective study in Southern Sweden.
14746861
2004
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Mutational analysis of BRCA1 and BRCA2 and clinicopathologic analysis of ovarian cancer in 82 ovarian cancer families: two common founder mutations of BRCA1 in Japanese population.
11595708
2001
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Comprehensive prediction of mRNA splicing effects of BRCA1 and BRCA2 variants.
21523855
2011
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
A high-throughput functional complementation assay for classification of BRCA1 missense variants.
23867111
2013
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.
25525159
2015
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Clinically applicable models to characterize BRCA1 and BRCA2 variants of uncertain significance.
18824701
2008
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Classification of missense substitutions in the BRCA genes: a database dedicated to Ex-UVs.
21990165
2012
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
A computational method to classify variants of uncertain significance using functional assay data with application to BRCA1.
21447777
2011
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
BRCT domains: phosphopeptide binding and signaling modules.
18508631
2008
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results.
18951446
2008