×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of ovary
0.700
GeneticVariation
BEFREE
A cell line from a human ovarian carcinoma with amplification of the K-ras gene.
3756872 1986
×
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Malignant neoplasm of ovary
0.400
Biomarker
BEFREE
These results indicate that the amount of CA125 in the serum is a good marker for detecting early stages of ovarian cancer and in particular for the evaluation of anticancer drugs.
2435620 1987
×
Entrez Id: 4012
Gene Symbol: LNPEP
LNPEP
Malignant neoplasm of ovary
0.020
Biomarker
BEFREE
At present, the measurement of PLAP has its greatest utility as a tumor marker in seminoma and ovarian cancer .
3325192 1987
×
Entrez Id: 250
Gene Symbol: ALPP
ALPP
Malignant neoplasm of ovary
0.010
Biomarker
BEFREE
At present, the measurement of PLAP has its greatest utility as a tumor marker in seminoma and ovarian cancer .
3325192 1987
×
Entrez Id: 9373
Gene Symbol: PLAA
PLAA
Malignant neoplasm of ovary
0.010
Biomarker
BEFREE
At present, the measurement of PLAP has its greatest utility as a tumor marker in seminoma and ovarian cancer .
3325192 1987
×
Entrez Id: 1435
Gene Symbol: CSF1
CSF1
Malignant neoplasm of ovary
0.090
AlteredExpression
BEFREE
Two of three human ovarian carcinoma cell-lines expressed multiple species of CSF-1 mRNA.
2973787 1988
×
Entrez Id: 5154
Gene Symbol: PDGFA
PDGFA
Malignant neoplasm of ovary
0.010
AlteredExpression
BEFREE
Of the 12 cell lines tested, 9, derived from breast, lung, gastric, and ovarian carcinomas , were found to express both PDGF-1 and PDGF-2 genes.
2844850 1988
×
Entrez Id: 3240
Gene Symbol: HP
HP
Malignant neoplasm of ovary
0.010
Biomarker
BEFREE
Haptoglobin groups in ovarian carcinoma .3397071 1988
×
Entrez Id: 4043
Gene Symbol: LRPAP1
LRPAP1
Malignant neoplasm of ovary
0.010
Biomarker
BEFREE
The monoclonal antibody RAP 5 immunoreactive with the ras gene product p21 was used in an immunohistochemical study of 57 patients with advanced ovarian cancer and in 28 normal ovaries.
3276289 1988
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of ovary
0.700
GeneticVariation
BEFREE
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer .
2470152 1989
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of ovary
0.700
Biomarker
BEFREE
The results suggest that amplification of the c-erb B-2/neu gene may play a role in the pathogenesis of ovarian carcinoma .
2569708 1989
×
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Malignant neoplasm of ovary
0.100
Biomarker
BEFREE
The demonstration of elevated P-glycoprotein in ovarian carcinomas indicates that P-glycoprotein overexpression is not limited to experimental tumor models.
2653233 1989
×
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Malignant neoplasm of ovary
0.100
AlteredExpression
BEFREE
P-glycoprotein expression in multidrug-resistant human ovarian carcinoma cell lines.2565764 1989
×
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Malignant neoplasm of ovary
0.100
AlteredExpression
BEFREE
These results favor the expression of the MDR1 gene as one of the determinants involved in the acquired chemoresistance of ovarian cancers .
2766278 1989
×
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
Malignant neoplasm of ovary
0.100
AlteredExpression
BEFREE
These results favor the expression of the MDR1 gene as one of the determinants involved in the acquired chemoresistance of ovarian cancers .
2766278 1989
×
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
Malignant neoplasm of ovary
0.050
AlteredExpression
BEFREE
Thus far, the types of carcinomas with which abnormal TGF-alpha expression has been associated include liver, gastrointestinal, breast, skin, lung, brain and ovarian cancers .
2696564 1989
×
Entrez Id: 4758
Gene Symbol: NEU1
NEU1
Malignant neoplasm of ovary
0.050
Biomarker
BEFREE
The results suggest that amplification of the c-erb B-2/neu gene may play a role in the pathogenesis of ovarian carcinoma .
2569708 1989
×
Entrez Id: 9148
Gene Symbol: NEURL1
NEURL1
Malignant neoplasm of ovary
0.040
Biomarker
BEFREE
The results suggest that amplification of the c-erb B-2/neu gene may play a role in the pathogenesis of ovarian carcinoma .
2569708 1989
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Malignant neoplasm of ovary
0.040
GeneticVariation
BEFREE
To determine whether loss of heterozygosity occurs at the c-Ha-ras1 locus in uncultured human ovarian carcinomas we used Southern blot analysis to study DNA from 17 pairs of ovarian tumors and matched white blood cell samples from the same patients.
2917352 1989
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of ovary
0.700
Biomarker
BEFREE
Although the human neu gene was shown to be amplified/overexpressed in a large portion of human breast and ovarian cancer , no reports indicate that the human neu gene is activated by a point mutation in human tumor.
2206283 1990
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of ovary
0.700
AlteredExpression
BEFREE
HER-2/neu overexpression was observed in 6/22 of mammary carcinomas (27%) and 7/14 of ovarian carcinomas (50%).1699198 1990
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of ovary
0.700
AlteredExpression
BEFREE
c-erbB-2 oncogene expression in ovarian cancer .
2266460 1990
×
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
Malignant neoplasm of ovary
0.600
AlteredExpression
BEFREE
There was a poor correlation between estrogen receptor and pS2 mRNA in ovarian carcinomas .
2306733 1990
×
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
Malignant neoplasm of ovary
0.400
Biomarker
BEFREE
This indicates that EGF-R + and those carcinomas expressing high amounts of c-myc constitute a more aggressive group of ovarian carcinomas .
2285597 1990
×
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
Malignant neoplasm of ovary
0.100
AlteredExpression
BEFREE
Although drug resistance is a major problem in treatment of ovarian cancer , resistance to the drugs most active against these tumors probably occurs through a mechanism other than expression of the MDR1 gene product.
1973872 1990