Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160

2012

Entrez Id: 2645
Gene Symbol: GCK
GCK
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160

2012

Entrez Id: 389421
Gene Symbol: LIN28B
LIN28B
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.900 GeneticVariation GWASDB Taken together, these data show that common variants in HACE1 and LIN28B influence neuroblastoma susceptibility and indicate that both genes likely have a role in disease progression. 22941191

2012

Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900 GeneticVariation GWASDB A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. 21980299

2011

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. 21647700

2011

Entrez Id: 3664
Gene Symbol: IRF6
IRF6
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
0.900 GeneticVariation GWASDB SNPs near two genes not previously associated with cleft lip with and without cleft palate (MAFB, most significant SNP rs13041247, with odds ratio (OR) per minor allele = 0.704, 95% CI 0.635-0.778, P = 1.44 x 10(-11); and ABCA4, most significant SNP rs560426, with OR = 1.432, 95% CI 1.292-1.587, P = 5.01 x 10(-12)) and two previously identified regions (at chromosome 8q24 and IRF6) attained genome-wide significance. 20436469

2010

Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900 GeneticVariation GWASDB Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480

2009

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. 19056611

2009

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 18372903

2008

Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900 GeneticVariation GWASDB A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. 17632545

2007

Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900 GeneticVariation GWASDB Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. 17554260

2007

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 17463249

2007

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900 GeneticVariation GWASDB A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 17463248

2007

Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
Diabetes Mellitus, Non-Insulin-Dependent
0.800 GeneticVariation GWASDB Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.800 GeneticVariation GWASDB We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)). 24880342

2014

Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
0.800 GeneticVariation GWASDB Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat. 23587638

2013

Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
0.800 GeneticVariation GWASDB Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. 22959728

2013

Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
Diabetes Mellitus, Non-Insulin-Dependent
0.800 GeneticVariation GWASDB A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. 22961080

2013

Entrez Id: 6336
Gene Symbol: SCN10A
SCN10A
CUI: C1142166
Disease: Brugada Syndrome (disorder)
Brugada Syndrome (disorder)
0.800 GeneticVariation GWASDB Through a genome-wide association study of 312 individuals with Brugada syndrome and 1,115 controls, we detected 2 significant association signals at the SCN10A locus (rs10428132) and near the HEY2 gene (rs9388451). 23872634

2013

Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
Diabetes Mellitus, Non-Insulin-Dependent
0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160

2012