×
Entrez Id:
6927
Gene Symbol:
HNF1A
HNF1A
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
22325160
2012
×
Entrez Id:
2645
Gene Symbol:
GCK
GCK
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
22885922
2012
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
22885922
2012
×
Entrez Id:
6927
Gene Symbol:
HNF1A
HNF1A
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
22885922
2012
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
22325160
2012
×
Entrez Id:
389421
Gene Symbol:
LIN28B
LIN28B
Neuroblastoma
0.900
GeneticVariation
GWASDB
Taken together, these data show that common variants in HACE1 and LIN28B influence neuroblastoma susceptibility and indicate that both genes likely have a role in disease progression.
22941191
2012
×
Entrez Id:
26191
Gene Symbol:
PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900
GeneticVariation
GWASDB
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
21980299
2011
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
22158537
2011
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
21647700
2011
×
Entrez Id:
3664
Gene Symbol:
IRF6
IRF6
Cleft upper lip
0.900
GeneticVariation
GWASDB
SNPs near two genes not previously associated with cleft lip with and without cleft palate (MAFB, most significant SNP rs13041247, with odds ratio (OR) per minor allele = 0.704, 95% CI 0.635-0.778, P = 1.44 x 10(-11); and ABCA4, most significant SNP rs560426, with OR = 1.432, 95% CI 1.292-1.587, P = 5.01 x 10(-12)) and two previously identified regions (at chromosome 8q24 and IRF6 ) attained genome-wide significance.
20436469
2010
×
Entrez Id:
26191
Gene Symbol:
PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900
GeneticVariation
GWASDB
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
19430480
2009
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
19056611
2009
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
18372903
2008
×
Entrez Id:
26191
Gene Symbol:
PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900
GeneticVariation
GWASDB
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
17632545
2007
×
Entrez Id:
26191
Gene Symbol:
PTPN22
PTPN22
Diabetes Mellitus, Insulin-Dependent
0.900
GeneticVariation
GWASDB
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
17554260
2007
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
17463246
2007
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
17463249
2007
×
Entrez Id:
3767
Gene Symbol:
KCNJ11
KCNJ11
Diabetes Mellitus, Non-Insulin-Dependent
0.900
GeneticVariation
GWASDB
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
17463248
2007
×
Entrez Id:
6928
Gene Symbol:
HNF1B
HNF1B
Diabetes Mellitus, Non-Insulin-Dependent
0.800
GeneticVariation
GWASDB
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
24509480
2014
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of lung
0.800
GeneticVariation
GWASDB
We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)).
24880342
2014
×
Entrez Id:
203228
Gene Symbol:
C9orf72
C9orf72
Amyotrophic Lateral Sclerosis
0.800
GeneticVariation
GWASDB
Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.
23587638
2013
×
Entrez Id:
203228
Gene Symbol:
C9orf72
C9orf72
Amyotrophic Lateral Sclerosis
0.800
GeneticVariation
GWASDB
Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.
22959728
2013
×
Entrez Id:
6928
Gene Symbol:
HNF1B
HNF1B
Diabetes Mellitus, Non-Insulin-Dependent
0.800
GeneticVariation
GWASDB
A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
22961080
2013
×
Entrez Id:
6336
Gene Symbol:
SCN10A
SCN10A
Brugada Syndrome (disorder)
0.800
GeneticVariation
GWASDB
Through a genome-wide association study of 312 individuals with Brugada syndrome and 1,115 controls, we detected 2 significant association signals at the SCN10A locus (rs10428132) and near the HEY2 gene (rs9388451).
23872634
2013
×
Entrez Id:
6928
Gene Symbol:
HNF1B
HNF1B
Diabetes Mellitus, Non-Insulin-Dependent
0.800
GeneticVariation
GWASDB
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
22325160
2012