Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.510 Biomarker CTD_human CCR3, CCR2A and macrophage inflammatory protein (MIP)-1a, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE) . 19490431

2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.510 Biomarker CTD_human In this work CCR2 and CCL2 expression were examined following status epilepticus (SE) induced by pilocarpine injection. 20034406

2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0020517
Disease: Hypersensitivity
Hypersensitivity 		0.500 Biomarker CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0020517
Disease: Hypersensitivity
Hypersensitivity 		0.500 Biomarker CTD_human Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants. 15585374

2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.500 Biomarker CTD_human Soluble CD40 ligand in pulmonary arterial hypertension: possible pathogenic role of the interaction between platelets and endothelial cells. 15302794

2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.500 Biomarker CTD_human We performed this study to evaluate the role of MCP-1 for the pathogenesis of PH in experimental CDH. 30418988

2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 Biomarker CTD_human Anti-monocyte chemoattractant protein-1 gene therapy prevents dimethylnitrosamine-induced hepatic fibrosis in rats. 15492853

2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury 		0.500 Biomarker CTD_human Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. 12087064

2002
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.500 Biomarker CTD_human Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets. 12468449

2002
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.500 Biomarker CTD_human Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. 15829914

2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0037926
Disease: Compression of spinal cord
Compression of spinal cord 		0.500 Biomarker CTD_human Nicotine attenuates oxidative stress, activation of redox-regulated transcription factors and induction of proinflammatory genes in compressive spinal cord trauma. 15135227

2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0085129
Disease: Bronchial Hyperreactivity
Bronchial Hyperreactivity 		0.500 Biomarker CTD_human Leukotrienes, IL-13, and chemokines cooperate to induce BHR and mucus in allergic mouse lungs. 12388339

2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0887898
Disease: Experimental Lung Inflammation
Experimental Lung Inflammation 		0.500 Biomarker CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0917798
Disease: Cerebral Ischemia
Cerebral Ischemia 		0.500 Biomarker CTD_human Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. 17394460

2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0917798
Disease: Cerebral Ischemia
Cerebral Ischemia 		0.500 Biomarker CTD_human Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. 15829914

2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.500 Biomarker CTD_human Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants. 15585374

2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.500 Biomarker CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker CTD_human Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects. 12928151

2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker CTD_human Atheroprotective Mechanisms Activated by Fluid Shear Stress in Endothelial Cells. 12677255

2002
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker CTD_human Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. 20720404

2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 Biomarker CTD_human Focal adhesion kinase knockdown in carcinoma-associated fibroblasts inhibits oral squamous cell carcinoma metastasis via downregulating MCP-1/CCL2 expression. 25199511

2015
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.400 Biomarker CTD_human Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production. 16332659

2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.400 Biomarker CTD_human

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.400 Biomarker CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695

2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.400 Biomarker CTD_human Patients with schizophrenia show raised serum levels of the pro-inflammatory chemokine CCL2: association with the metabolic syndrome in patients? 18486454

2008