DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Malignant neoplasm of breast ×

Gene: PPM1D ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	8493
Gene Symbol:	PPM1D

PPM1D

CUI:	C0006142
Disease:	Malignant neoplasm of breast

Malignant neoplasm of breast

0.600

Biomarker

BEFREE

Here we explored the role of PPM1D aberrations in primary breast cancer.

16254685

2006

Entrez Id:	8493
Gene Symbol:	PPM1D

PPM1D

CUI:	C0006142
Disease:	Malignant neoplasm of breast

Malignant neoplasm of breast

0.600

PosttranslationalModification

BEFREE

In vitro, inactivation of Wip1 reduces the proliferation rate of breast cancer cell lines and enhances growth inhibition caused by doxorubicin.

16258255

2005

Entrez Id:	8493
Gene Symbol:	PPM1D

PPM1D

CUI:	C0006142
Disease:	Malignant neoplasm of breast

Malignant neoplasm of breast

0.600

Biomarker

BEFREE

Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23.

12021784

2002

Entrez Id:	8493
Gene Symbol:	PPM1D

PPM1D

CUI:	C0006142
Disease:	Malignant neoplasm of breast

Malignant neoplasm of breast

0.600

Biomarker

CTD_human

Entrez Id:	8493
Gene Symbol:	PPM1D

PPM1D

CUI:	C0006142
Disease:	Malignant neoplasm of breast

Malignant neoplasm of breast

0.600

Biomarker

GENOMICS_ENGLAND