Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0018203
Disease: Chronic granulomatous disease
Chronic granulomatous disease 		0.100 Biomarker BEFREE Specifically, macrophage-activating cytokines such as interferon gamma (IFNγ) and granulocyte colony-stimulating factor (GM-CSF) are commercially available immune potentiators used to prevent infections in patients with chronic granulomatous disease and febrile neutropenia, respectively. 28558308

2017
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0018203
Disease: Chronic granulomatous disease
Chronic granulomatous disease 		0.100 Biomarker BEFREE Recombinant human interferon-gamma reconstitutes defective phagocyte function in patients with chronic granulomatous disease of childhood. 2838849

1988
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0018203
Disease: Chronic granulomatous disease
Chronic granulomatous disease 		0.100 Biomarker BEFREE This work expands the genetic spectrum of X-linked CGD and demonstrates improvement in macrophage function in X91<sup>+</sup>CGD patient by rhIFN-γ. 27666509

2016
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0018203
Disease: Chronic granulomatous disease
Chronic granulomatous disease 		0.100 Biomarker BEFREE This study demonstrates partial correction of the cellular defects in chronic granulomatous disease by interferon gamma and provides a basis for clinical trials of the agent. 2838754

1988
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0018203
Disease: Chronic granulomatous disease
Chronic granulomatous disease 		0.100 Biomarker BEFREE During the international placebo-controlled trial on the efficacy of interferon-gamma (IFN-gamma) in chronic granulomatous disease (CGD), 19 patients entered the study via our Institute. 8975873

1996