Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 Biomarker BEFREE High rate of FGFR1 amplifications in brain metastases of squamous and non-squamous lung cancer. 24183471

2014
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 AlteredExpression BEFREE We identified four cell lines and two newly established primary lung cancer cultures that showed high FGFR1 expression levels, and evaluated the effect of the novel FGFR1 inhibitor ponatinib on cell growth. 23563700

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 Biomarker BEFREE This study provides novel epidemiologic data through identification of FGFR1 gene amplification in Chinese NSCLC specimens (particularly squamous) and, importantly, extends the clinical significance of this finding by using multiple FGFR1-amplified squamous lung cancer PDTX models to show tumor stasis or regression effects using a specific FGFR inhibitor (AZD4547). 23082000

2012
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 GeneticVariation BEFREE An increased FGFR1 gene copy number was found in 32 (32%) lung cancer patients. 22179561

2012
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.100 Biomarker BEFREE To evaluate the significance of FGFR1 in lung cancer, we analysed tumours by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). 22648708

2012