Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.600 AlteredExpression BEFREE An MLL gene rearrangement and MLL-CBP chimeric mRNA were found in AML, but not in ALL. 10679915

2000
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.600 GeneticVariation BEFREE CBP, which is located on 16p13 and encodes a transcriptional adaptor/coactivator protein, has been shown to fuse by the t(8;16)(p11;p13) translocation to MOZ on 8p11 in acute myeloid leukemia. 9290955

1997
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.600 GeneticVariation BEFREE We applied fluorescence in situ hybridization (FISH) and Southern blot analyses to a series of AML patients with a t(8;16) and detected DNA rearrangements of both the CBP and the MOZ loci in all cases tested. 9447825

1997
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.600 GeneticVariation BEFREE Intriguingly, mutations in the CBP gene are responsible for RTS as well as the t(8;16)-associated AML. 9177780

1997
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.600 Biomarker BEFREE Our results combined with the finding of the MOZ-CBP fusion in t(8;16)-AML suggest that the CBP gene may be associated with leukemogenesis through translocations. 9166831

1997
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.600 GeneticVariation BEFREE The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. 8782817

1996