Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker BEFREE The purpose of this study was to investigate the mechanistic role of CCL2 in prostate cancer growth in bone. 19176388

2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker BEFREE The relationship between CCL2 and curcumin, however, has not been studied in PCa. 19360344

2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker BEFREE These data suggest a role for HBME-secreted CCL2 in promoting PCa cell extravasation into the bone microenvironment. 18646053

2008
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker BEFREE These findings indicate that combination therapies targeting T/E fusion, NF-kB, CCL2 and/or AKT pathways may have efficacy in T/E fusion gene expressing PCa. 25749044

2015
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker BEFREE These findings strengthen the rationale for future efforts to determine whether targeting the PPARγ-adiponectin-MCP-1 axis will decrease periprostatic adipose inflammation and thereby reduce the risk of high-grade prostate cancer or improve outcomes for men with prostate cancer.<i></i>. 29222347

2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation BEFREE These results support the influence of CCL2 variants on prostate cancer development and progression. 21135144

2011
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 Biomarker BEFREE To characterize the physiological function of MCP-1 in the CM, we performed an MTT-assay, a wound-healing and invasion assay with anti-MCP-1 antibody using three prostate cancer cell lines: DU145, LNCaP, and PC-3. 25917126

2015
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.100 GeneticVariation BEFREE We observed a significantly enhanced risk for PCa due to interaction between CCL2 I/D, -2518 (A > G), and CCR2 (G > A) genotypes. 25266801

2015