Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 Biomarker BEFREE These results indicated the important roles of TGFB1, TGFBR1 and EGF in the pathogenesis of PC. 27035876

2016
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 AlteredExpression BEFREE microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions. 28604742

2017
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 Biomarker BEFREE CRT promotes EGF-induced EMT in PC cells via Integrin/EGFR-ERK/MAPK signaling pathway, which would be a promising therapy target for PC. 29072694

2017
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 AlteredExpression BEFREE The abnormally elevated expression of EGF and TGF-α are closely associated with the occurrence and development of chronic pancreatitis and pancreatic cancer. 29125273

2018
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 Biomarker BEFREE miR-21 promotes EGF-induced pancreatic cancer cell proliferation by targeting Spry2. 30464258

2018
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 AlteredExpression BEFREE Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway. 30968148

2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 Biomarker BEFREE Long non-coding RNA XIST regulates the EGF receptor to promote TGF-β1-induced epithelial-mesenchymal transition in pancreatic cancer. 31013436

2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.100 Biomarker BEFREE The efficacy of epidermal growth factor (EGF) receptor (EGFR) inhibitors in patients with non-small cell lung cancer (NSCLC), pancreatic cancer (PC), or colorectal cancer (CRC) has been demonstrated. 31492766

2020