×
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
Diabetes Mellitus, Non-Insulin-Dependent
0.300
Biomarker
CTD_human
Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects.
16959961 2006
×
Entrez Id: 10018
Gene Symbol: BCL2L11
BCL2L11
Diabetes Mellitus, Non-Insulin-Dependent
0.300
Biomarker
CTD_human
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
28869590 2017
×
Entrez Id: 635
Gene Symbol: BHMT
BHMT
Diabetes Mellitus, Non-Insulin-Dependent
0.300
Biomarker
CTD_human
Alterations in hepatic metabolism of sulfur amino acids in non-obese type-2 diabetic Goto-Kakizaki rats.
23665415 2013
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Diabetes Mellitus, Non-Insulin-Dependent
0.400
Biomarker
CTD_human
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
28869590 2017
×
Entrez Id: 145741
Gene Symbol: C2CD4A
C2CD4A
Diabetes Mellitus, Non-Insulin-Dependent
0.340
Biomarker
CTD_human
In conclusion, we identified two new loci at UBE2E2 and C2CD4A -C2CD4B associated with susceptibility to T2D .
20818381 2010
×
Entrez Id: 388125
Gene Symbol: C2CD4B
C2CD4B
Diabetes Mellitus, Non-Insulin-Dependent
0.330
Biomarker
CTD_human
In conclusion, we identified two new loci at UBE2E2 and C2CD4A-C2CD4B associated with susceptibility to T2D .
20818381 2010
×
Entrez Id: 718
Gene Symbol: C3
C3
Diabetes Mellitus, Non-Insulin-Dependent
0.330
Biomarker
CTD_human
Traffic-related air pollution and incident type 2 diabetes: results from the SALIA cohort study.
20504758 2010
×
Entrez Id: 11132
Gene Symbol: CAPN10
CAPN10
Diabetes Mellitus, Non-Insulin-Dependent
0.700
Biomarker
CTD_human
In the present work we evaluated if CAPN-10 SNPs and iAs exposure jointly contribute to the outcome of T2DM .
23349674 2013
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Diabetes Mellitus, Non-Insulin-Dependent
0.390
Biomarker
CTD_human
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.
15531508 2004
×
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Diabetes Mellitus, Non-Insulin-Dependent
0.300
Biomarker
CTD_human
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.
15531508 2004
×
Entrez Id: 847
Gene Symbol: CAT
CAT
Diabetes Mellitus, Non-Insulin-Dependent
0.400
Therapeutic
CTD_human
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.
15531508 2004
×
Entrez Id: 847
Gene Symbol: CAT
CAT
Diabetes Mellitus, Non-Insulin-Dependent
0.400
Biomarker
CTD_human
Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes .15111504 2004
×
Entrez Id: 847
Gene Symbol: CAT
CAT
Diabetes Mellitus, Non-Insulin-Dependent
0.400
Therapeutic
CTD_human
Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes .15111504 2004
×
Entrez Id: 847
Gene Symbol: CAT
CAT
Diabetes Mellitus, Non-Insulin-Dependent
0.400
Biomarker
CTD_human
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.
15531508 2004
×
Entrez Id: 875
Gene Symbol: CBS
CBS
Diabetes Mellitus, Non-Insulin-Dependent
0.320
Biomarker
CTD_human
Alterations in hepatic metabolism of sulfur amino acids in non-obese type-2 diabetic Goto-Kakizaki rats.
23665415 2013
×
Entrez Id: 80212
Gene Symbol: CCDC92
CCDC92
Diabetes Mellitus, Non-Insulin-Dependent
0.310
Biomarker
CTD_human
Joint T2D -CHD analysis identified eight variants-two of which are coding-where T2D and CHD associations appear to colocalize, including a new joint T2D -CHD association at the CCDC92 locus that also replicated for T2D .
28869590 2017
×
Entrez Id: 894
Gene Symbol: CCND2
CCND2
Diabetes Mellitus, Non-Insulin-Dependent
0.420
Biomarker
CTD_human
A low-frequency (1.47%) variant in intron 1 of CCND2 , rs76895963[G], reduces risk of T2D by half (odds ratio (OR) = 0.53, P = 5.0 × 10(-21)) and is correlated with increased CCND2 expression.
24464100 2014
×
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700
Biomarker
CTD_human
In addition to confirming two recently identified risk variants, we identified a variant in the CDKAL1 gene that was associated with T2D in individuals of European ancestry (allele-specific odds ratio (OR) = 1.20 (95% confidence interval, 1.13-1.27), P = 7.7 x 10(-9)) and individuals from Hong Kong of Han Chinese ancestry (OR = 1.25 (1.11-1.40), P = 0.00018).
17460697 2007
×
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700
Biomarker
CTD_human
Bayesian refinement of association signals for 14 loci in 3 common diseases.
23104008 2012
×
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700
Biomarker
CTD_human
Five of the loci are known to be associated with other phenotypes: ADCY5 and CDKAL1 with type 2 diabetes , ADRB1 with adult blood pressure and HMGA2 and LCORL with adult height.
23202124 2013
×
Entrez Id: 1036
Gene Symbol: CDO1
CDO1
Diabetes Mellitus, Non-Insulin-Dependent
0.300
Biomarker
CTD_human
Alterations in hepatic metabolism of sulfur amino acids in non-obese type-2 diabetic Goto-Kakizaki rats.
23665415 2013
×
Entrez Id: 493856
Gene Symbol: CISD2
CISD2
Diabetes Mellitus, Non-Insulin-Dependent
0.320
Biomarker
CTD_human
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
28869590 2017
×
Entrez Id: 80790
Gene Symbol: CMIP
CMIP
Diabetes Mellitus, Non-Insulin-Dependent
0.430
Biomarker
CTD_human
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
28869590 2017
×
Entrez Id: 22866
Gene Symbol: CNKSR2
CNKSR2
Diabetes Mellitus, Non-Insulin-Dependent
0.400
Biomarker
CTD_human
Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
30718926 2019
×
Entrez Id: 1374
Gene Symbol: CPT1A
CPT1A
Diabetes Mellitus, Non-Insulin-Dependent
0.560
Biomarker
CTD_human
Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes.
16123366 2005