×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Identification of a one-base germline deletion (codon 888 del C) and an intron splice acceptor site polymorphism in hMSH2.
9222765 1997
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Hereditary nonpolyposis colorectal cancer (HNPCC): eight novel germline mutations in hMSH2 or hMLH1 genes.
9298827 1997
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
9311737 1997
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
MLH1 and MSH2 constitutional mutations in colorectal cancer families not meeting the standard criteria for hereditary nonpolyposis colorectal cancer.
9506527 1998
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Novel germline mutations of hMSH2 in a patient with hereditary nonpolyposis colorectal cancer (HNPCC) and in a patient with six primary cancers.
9621522 1998
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
9718327 1998
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer.
9774676 1998
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
9777949 1998
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.
10077621 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Reduction in hMSH2 mRNA levels by premature translation termination: implications for mutation screening in hereditary nonpolyposis colorectal cancer.
10080150 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium.
10196371 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer.
10323887 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer.
10375096 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Predominant germ-line mutation of the hMSH2 gene in Japanese hereditary non-polyposis colorectal cancer kindreds.
10404063 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Frequent microsatellite instability and mismatch repair gene mutations in young Chinese patients with colorectal cancer.
10413423 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing.
10422993 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Evaluation of the replication error phenotype in relation to molecular and clinicopathological features in hereditary and early onset colorectal cancer.
10448273 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer.
10480359 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Various mutation screening techniques in the DNA mismatch repair genes hMSH2 and hMLH1.
10495924 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous-tail removal during recombination.
10523644 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening.
10528862 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
[Muir-Torre syndrome and familial colorectal cancer: 2 families with molecular genetic analysis].
10530344 1999
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Microsatellite instability as a predictor of a mutation in a DNA mismatch repair gene in familial colorectal cancer.
10564582 2000
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families.
10612836 2000
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Detection of mutations in mismatch repair genes in Portuguese families with hereditary non-polyposis colorectal cancer (HNPCC) by a multi-method approach.
10713887 2000