Source: GWASCAT

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT Identification of a new locus at 16q12 associated with time to asthma onset. 27130862

2016
Entrez Id: 55876
Gene Symbol: GSDMB
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma. 27439200

2016
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013

2014
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. 23028483

2012
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT Four were at previously reported loci on 17q21, near IL1RL1, TSLP and IL33, but we report for the first time, to our knowledge, that these loci are associated with asthma risk in three ethnic groups. 21804549

2011
Entrez Id: 55876
Gene Symbol: GSDMB
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
Entrez Id: 55876
Gene Symbol: GSDMB
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503

2010
Entrez Id: 55876
Gene Symbol: GSDMB
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		0.500 GeneticVariation GWASCAT Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. 17611496

2007
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738

2019
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. 31036433

2019
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474

2019
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011

2018
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Identification of a new locus at 16q12 associated with time to asthma onset. 27130862

2016
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. 23181788

2012
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0004096
Disease: Asthma
Asthma 		0.490 GeneticVariation GWASCAT Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864

2011
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
CUI: C0004096
Disease: Asthma
Asthma 		0.480 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738

2019
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
CUI: C0004096
Disease: Asthma
Asthma 		0.480 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011

2018
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
CUI: C0004096
Disease: Asthma
Asthma 		0.480 GeneticVariation GWASCAT Identification of Four Novel Loci in Asthma in European American and African American Populations. 27611488

2017
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
CUI: C0004096
Disease: Asthma
Asthma 		0.480 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
CUI: C0004096
Disease: Asthma
Asthma 		0.480 GeneticVariation GWASCAT Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. 20159242

2010
Entrez Id: 5144
Gene Symbol: PDE4D
PDE4D
CUI: C0004096
Disease: Asthma
Asthma 		0.470 GeneticVariation GWASCAT The phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) gene (PDE4D) is a regulator of airway smooth-muscle contractility, and PDE4 inhibitors have been developed as medications for asthma. 19426955

2009
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
CUI: C0004096
Disease: Asthma
Asthma 		0.460 GeneticVariation GWASCAT Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. 30787307

2019