Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 25886
Gene Symbol: POC1A
POC1A
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.020 GeneticVariation BEFREE (Optical Coherence Tomography in Patients With Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease [SOFT-MI]; NCT02783963). 30343070

2019

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation BEFREE -308G>A and -1031T>C tumor necrosis factor gene polymorphisms in Tunisian patients with coronary artery disease. 19803813

2009

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation BEFREE -786T>C polymorphism of the endothelial nitric oxide synthase gene in Chilean subjects with coronary artery disease and controls. 17927970

2008

Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation BEFREE -94 ATTG insertion/deletion polymorphism of the NFKB1 gene is associated with coronary artery disease in Han and Uygur women in China. 24818816

2014

Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.080 GeneticVariation BEFREE 1.The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer. 19650794

2010

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation BEFREE 10-Year Associations Between Tumor Necrosis Factor Receptors 1 and 2 and Cardiovascular Events in Patients With Stable Coronary Heart Disease: A CLARICOR (Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease) Trial Substudy. 29686027

2018

Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.500 GeneticVariation BEFREE 14 association studies focusing on three polymorphisms (A379V, V279F and R92H) in PLA2G7 gene and risk of CHD were included in meta-analysis, covering a total of 8,280 cases and 5,656 controls. 20926117

2010

Entrez Id: 1118
Gene Symbol: CHIT1
CHIT1
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.010 GeneticVariation BEFREE 24 bp duplication of CHIT1 gene is not correlated with coronary artery disease in Corsica Island (France). 17916351

2007

Entrez Id: 760
Gene Symbol: CA2
CA2
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.040 Biomarker BEFREE 256 patients without a prior history of coronary artery disease had undergone a chest CT. CT images were reviewed to detect CAC. 30696608

2019

Entrez Id: 788
Gene Symbol: SLC25A20
SLC25A20
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.040 Biomarker BEFREE 256 patients without a prior history of coronary artery disease had undergone a chest CT. CT images were reviewed to detect CAC. 30696608

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation BEFREE 3 years) with chronic stable angina due to angiographically documented coronary artery disease, all of whom had failed conventional therapy (drugs, PTCA, and/or CABG), were treated with direct myocardial injection of phVEGF(165) via a minithoracotomy. 10961959

2000

Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 AlteredExpression BEFREE 3-hydroxy-3-methylglutaryl (HMG)-coenzyme A (CoA) reductase inhibitors, or statins, significantly reduce cardiovascular events and mortality in patients with or without coronary artery disease and reduce plasma CRP levels in humans. 15790934

2005

Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 Biomarker BEFREE 40 ACS subjects who had had a definite diagnosis of CHD for more than 2 years with no history of T2DM were recuited as the CACS group(chronic CHD with ACS group). 30670045

2019

Entrez Id: 84680
Gene Symbol: ACCS
ACCS
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 Biomarker BEFREE 40 ACS subjects who had had a definite diagnosis of CHD for more than 2 years with no history of T2DM were recuited as the CACS group(chronic CHD with ACS group). 30670045

2019

Entrez Id: 23659
Gene Symbol: PLA2G15
PLA2G15
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 Biomarker BEFREE 40 ACS subjects who had had a definite diagnosis of CHD for more than 2 years with no history of T2DM were recuited as the CACS group(chronic CHD with ACS group). 30670045

2019

Entrez Id: 338
Gene Symbol: APOB
APOB
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.500 GeneticVariation BEFREE 5' ins/del and 3' VNTR polymorphisms in the apolipoprotein B gene in relation to lipids and coronary artery disease. 18254714

2008

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker BEFREE 9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells. 26487755

2015

Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.020 Biomarker BEFREE 9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells. 26487755

2015

Entrez Id: 5972
Gene Symbol: REN
REN
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker BEFREE : The renin-angiotensin system plays an important role in the regulation of blood pressure and the development of coronary artery disease. 29474203

2018

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker BEFREE Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms. 10500308

1999

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.400 GeneticVariation BEFREE Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms. 10500308

1999

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.700 GeneticVariation BEFREE Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. 16682673

2006

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker BEFREE Coronary artery disease and depression: possible role of brain-derived neurotrophic factor and serotonin transporter gene polymorphisms. 19885623

2009

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.040 Biomarker BEFREE CHD in Chinese population is strongly associated with HLA-DRB1*01 and DRB1*04 haplotypes, and formation of CD4(+)CD28(null) T cells was related to HLA-DRB1*01, DRB1*04, and DRB1*15 alleles. 20842443

2011

Entrez Id: 129831
Gene Symbol: RBM45
RBM45
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.020 Biomarker BEFREE CHD in Chinese population is strongly associated with HLA-DRB1*01 and DRB1*04 haplotypes, and formation of CD4(+)CD28(null) T cells was related to HLA-DRB1*01, DRB1*04, and DRB1*15 alleles. 20842443

2011