Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human HER2 expression and efficacy of dose-dense anthracycline-containing adjuvant chemotherapy in breast cancer patients. 15970926

2005

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human HER2 overexpression as a predictive marker in a randomized trial comparing adjuvant cyclophosphamide/methotrexate/5-fluorouracil with epirubicin in patients with stage I/II breast cancer: long-term results. 16137437

2005

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group. 16234514

2005

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Evaluation of the HER2/neu-derived peptide GP2 for use in a peptide-based breast cancer vaccine trial. 16596621

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Topoisomerase IIalpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401. 16682728

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. 16495393

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Evaluation of the HER2/neu-derived peptide GP2 for use in a peptide-based breast cancer vaccine trial. 16596621

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. 16495393

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Topoisomerase IIalpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401. 16682728

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Efficacy of high-dose alkylating chemotherapy in HER2/neu-negative breast cancer. 16446318

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Investigating the combination of trastuzumab and HER2/neu peptide vaccines for the treatment of breast cancer. 16865596

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Efficacy of high-dose alkylating chemotherapy in HER2/neu-negative breast cancer. 16446318

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Metastatic breast cancer: an updating. 16950593

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer. 16978400

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Investigating the combination of trastuzumab and HER2/neu peptide vaccines for the treatment of breast cancer. 16865596

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Metastatic breast cancer: an updating. 16950593

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer. 16978400

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer. 18086299

2007

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: the trastuzumab and vinorelbine or taxane study. 17614302

2007

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: the trastuzumab and vinorelbine or taxane study. 17614302

2007

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer. 18086299

2007

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial. 18768436

2008

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Therapeutic CTD_human [Efficacy and toxicity of trastuzumab combined vinorelbine in 21 patients with HER2 overexpressing metastatic breast cancer]. 18819904

2008

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial. 18768436

2008

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human [Efficacy and toxicity of trastuzumab combined vinorelbine in 21 patients with HER2 overexpressing metastatic breast cancer]. 18819904

2008