×
Entrez Id: 3164
Gene Symbol: NR4A1
NR4A1
Pancreatic carcinoma
0.050
AlteredExpression
BEFREE
1,1-Bis(3'-indolyl)-1-(p-anisyl)methane (DIM-C-pPhOCH3) activates the orphan receptor nerve growth factor-induced Balpha (Nur77 ) in cancer cells, and in this study, DIM-C-pPhOCH3 decreased Panc1 pancreatic cancer cell survival and arrested cells in G0-G1.
19584258 2009
×
Entrez Id: 10333
Gene Symbol: TLR6
TLR6
Pancreatic carcinoma
0.010
GeneticVariation
BEFREE
18 SNPs in 14 candidate genes (CSF2, DENND1B, DPP10, FLG, IL13, IL13RA2, LRP1B, NOD1, NPSR1, ORMDL3, RORA, STAT4, TLR6 , TRA) were significantly associated with pancreas cancer risk.
25945796 2015
×
Entrez Id: 6955
Gene Symbol: TRA
TRA
Pancreatic carcinoma
0.040
GeneticVariation
BEFREE
18 SNPs in 14 candidate genes (CSF2, DENND1B, DPP10, FLG, IL13, IL13RA2, LRP1B, NOD1, NPSR1, ORMDL3, RORA, STAT4, TLR6, TRA ) were significantly associated with pancreas cancer risk.
25945796 2015
×
Entrez Id: 573
Gene Symbol: BAG1
BAG1
Pancreatic carcinoma
0.020
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530 2019
×
Entrez Id: 5915
Gene Symbol: RARB
RARB
Pancreatic carcinoma
0.010
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530 2019
×
Entrez Id: 6294
Gene Symbol: SAFB
SAFB
Pancreatic carcinoma
0.010
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530 2019
×
Entrez Id: 10313
Gene Symbol: RTN3
RTN3
Pancreatic carcinoma
0.010
Biomarker
BEFREE
4-HAP also reduced liver metastases in human pancreatic cancer -bearing nude mice.
31358530 2019
×
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
Pancreatic carcinoma
0.090
GeneticVariation
BEFREE
5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer .
15941958 2005
×
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
Pancreatic carcinoma
0.040
Biomarker
BEFREE
5-FU resistant EMT -like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.
29258566 2017
×
Entrez Id: 3702
Gene Symbol: ITK
ITK
Pancreatic carcinoma
0.020
Biomarker
BEFREE
5-FU resistant EMT -like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.
29258566 2017
×
Entrez Id: 2022
Gene Symbol: ENG
ENG
Pancreatic carcinoma
0.020
Biomarker
BEFREE
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin -targeting immunotoxin CD105-saporin.
29258566 2017
×
Entrez Id: 6382
Gene Symbol: SDC1
SDC1
Pancreatic carcinoma
0.040
AlteredExpression
BEFREE
Pancreatic cancer cell lines expressed syndecan-1 mRNA and protein at variable levels.10962434 2000
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Pancreatic carcinoma
0.700
GeneticVariation
BEFREE
Pancreatic cancer exhibits a high frequency of K-ras gene mutations; however, it is not known whether DOC-2 expression is altered in these tumors.11406647 2001
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Pancreatic carcinoma
0.700
AlteredExpression
BEFREE
Pancreatic cancer is particularly resistant to apoptosis by antineoplastic agents, which is partly attributable to the lack of functional p53 .11585734 2001
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Pancreatic carcinoma
0.100
Biomarker
BEFREE
Pancreatic cancer cells are susceptible to antiproliferative effects of cytokines such as tumor necrosis factor-alpha (TNF-alpha ).11854621 2002
×
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
Pancreatic carcinoma
0.100
AlteredExpression
BEFREE
Pancreatic cancer is no exception; MMP-2 and MMP-9 show high levels of expression in clinical and experimental models.12167581 2002
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Pancreatic carcinoma
0.100
AlteredExpression
BEFREE
Pancreatic cancer is no exception; MMP-2 and MMP-9 show high levels of expression in clinical and experimental models.12167581 2002
×
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Pancreatic carcinoma
0.700
AlteredExpression
BEFREE
Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1.12619158 2003
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Pancreatic carcinoma
0.100
AlteredExpression
BEFREE
Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1 .12619158 2003
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Pancreatic carcinoma
0.400
GeneticVariation
BEFREE
Pancreatic cancer is seen in some breast cancer families with BRCA1 and BRCA2 mutations.12670518 2003
×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Pancreatic carcinoma
0.400
GeneticVariation
BEFREE
Pancreatic cancer is seen in some breast cancer families with BRCA1 and BRCA2 mutations.12670518 2003
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Pancreatic carcinoma
0.600
GeneticVariation
BEFREE
Pancreatic carcinoma in carriers of a specific 19 base pair deletion of CDKN2A /p16 (p16-leiden).14506146 2003
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Pancreatic carcinoma
0.700
GeneticVariation
BEFREE
Pancreatic cancer is usually initiated by mutation of KRAS and aberrant expression of SHH.16367914 2006
×
Entrez Id: 6469
Gene Symbol: SHH
SHH
Pancreatic carcinoma
0.040
AlteredExpression
BEFREE
Pancreatic cancer is usually initiated by mutation of KRAS and aberrant expression of SHH .16367914 2006
×
Entrez Id: 283297
Gene Symbol: OR10A4
OR10A4
Pancreatic carcinoma
0.010
Biomarker
BEFREE
Pancreatic cancer had a higher frequency of Hp2 -2 phenotype but lacked Hp1-1 phenotype.17414053 2007