×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A genotype-phenotype correlation in HNPCC: strong predominance of msh2 mutations in 41 patients with Muir-Torre syndrome.
15235030
2004
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A high incidence of MSH6 mutations in Amsterdam criteria II-negative families tested in a diagnostic setting.
18625694
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Cancer
1.000
CausalMutation
CLINVAR
A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple café-au-lait spots.
11809679
2002
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple café-au-lait spots.
11809679
2002
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Cancer
1.000
CausalMutation
CLINVAR
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
18561205
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
GeneticVariation
CLINVAR
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
18561205
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
18561205
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes.
24689082
2014
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening.
10528862
1999
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
A modified multiplex PCR assay for detection of large deletions in MSH2 and MLH1.
11857745
2002
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients.
28445943
2017
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Cancer
1.000
CausalMutation
CLINVAR
A mononucleotide markers panel to identify hMLH1/hMSH2 germline mutations.
17473388
2007
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
A mononucleotide markers panel to identify hMLH1/hMSH2 germline mutations.
17473388
2007
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A mononucleotide markers panel to identify hMLH1/hMSH2 germline mutations.
17473388
2007
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
GeneticVariation
CLINVAR
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
22949379
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
22949379
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
22949379
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.
22949379
2013
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
A new mutation in the hMSH2 gene in a Spanish Lynch syndrome family.
21156417
2010
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A new strategy to screen MMR genes in Lynch Syndrome: HA-CAE, MLPA and RT-PCR.
19250818
2009
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
A novel MSH2 germline mutation in a Druze HNPCC family.
17661183
2008
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Cancer
1.000
CausalMutation
CLINVAR
A rapid and cell-free assay to test the activity of lynch syndrome -associated MSH2 and MSH6 missense variants.
22102614
2012
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
GeneticVariation
CLINVAR
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
22102614
2012
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Hereditary Nonpolyposis Colorectal Neoplasms
0.900
CausalMutation
CLINVAR
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
22102614
2012
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
Colorectal cancer, hereditary nonpolyposis, type 1
0.600
CausalMutation
CLINVAR
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants.
22102614
2012