Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.700 Biomarker BEFREE Our study is the first direct evidence that PIK3CA is an oncogene in ovarian cancer and greatly extends recent findings in breast cancer. 15520168

2004
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.700 Biomarker BEFREE The gene of phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) has been implicated as an oncogene in ovarian cancer [L. Shayesteh et al., Nat.Genet., 21: 99-102, 1999]. 12874030

2003
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.700 Biomarker BEFREE These data demonstrate that different repertoires of downstream signaling proteins, particularly those of the MEK6-p38 MAPK-CK2 pathway and the PI3K pathway, are correlated with phenotypic manifestations of a cell culture model of OSE at progressive stages in the development of ovarian cancer. 11531284

2001
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.700 Biomarker BEFREE Our observations suggest PIK3CA is an oncogene that has an important role in ovarian cancer. 9916799

1999