Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 AlteredExpression BEFREE Germline BRCA1/2 mutations and p27(Kip1) protein levels independently predict outcome after breast cancer. 11118465

2000
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 AlteredExpression BEFREE In epithelial cells of normal and benign breast disease, expression of p27Kip1 was well preserved while its expression markedly decreased in breast cancer (45 of 68). 10481943

1999
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 Biomarker BEFREE To address this question, here, we transfected the MCF7 breast cancer cell line and the MCF10F nontumorigenic mammary epithelial cell line with a vector containing the p27Kip1 cDNA to obtain derivatives that express increased levels of p27Kip1. 9699679

1998
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 Biomarker BEFREE Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer. 9018244

1997
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 AlteredExpression BEFREE Additional studies are required to determine why some breast cancer cells express relatively high levels of p27(Kip1) despite its known role as an inhibitor of cell cycle progression. 9815577

1997
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 GeneticVariation BEFREE p27/Kip1 mutation found in breast cancer. 8625318

1996
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 Biomarker BEFREE Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1 in primary breast carcinomas. 8557269

1996
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 CausalMutation CGI