Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.700 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019

Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.700 GeneticVariation GWASCAT Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. 23453885

2013

Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715

2011

Entrez Id: 27445
Gene Symbol: PCLO
PCLO
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.500 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

Entrez Id: 27445
Gene Symbol: PCLO
PCLO
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.500 GeneticVariation GWASCAT Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder. 28540843

2017

Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.500 GeneticVariation GWASCAT Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations. 24528284

2014

Entrez Id: 27445
Gene Symbol: PCLO
PCLO
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.500 GeneticVariation GWASCAT Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples. 21621269

2011

Entrez Id: 2915
Gene Symbol: GRM5
GRM5
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

Entrez Id: 2915
Gene Symbol: GRM5
GRM5
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 GeneticVariation GWASCAT Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways. 29662059

2018

Entrez Id: 2915
Gene Symbol: GRM5
GRM5
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085

2018

Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085

2018

Entrez Id: 2917
Gene Symbol: GRM7
GRM7
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.490 GeneticVariation GWASCAT On the basis of previous biological evidence, we consider GRM7 a strong MDD candidate gene. 20038947

2011

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation GWASCAT Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. 29700475

2018

Entrez Id: 1131
Gene Symbol: CHRM3
CHRM3
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.410 GeneticVariation GWASCAT GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort. 30219690

2019

Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.410 GeneticVariation GWASCAT A genome-wide association study of suicidal behavior. 26079190

2015

Entrez Id: 9771
Gene Symbol: RAPGEF5
RAPGEF5
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 GeneticVariation GWASCAT GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort. 30219690

2019

Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085

2018

Entrez Id: 8842
Gene Symbol: PROM1
PROM1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 GeneticVariation GWASCAT Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study. 24964207

2014

Entrez Id: 104909134
Gene Symbol: LINC02210-CRHR1
LINC02210-CRHR1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.150 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085

2018

Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.150 GeneticVariation GWASCAT Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs. 25944848

2015

Entrez Id: 91752
Gene Symbol: ZNF804A
ZNF804A
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.140 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019

Entrez Id: 1993
Gene Symbol: ELAVL2
ELAVL2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.130 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.130 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085

2018

Entrez Id: 1993
Gene Symbol: ELAVL2
ELAVL2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.130 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085

2018