×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
24816253
2014
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa.
19184424
2010
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families.
19168852
2009
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GermlineCausalMutation
ORPHANET
As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families.
19168852
2009
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families.
19168852
2009
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
UNIPROT
However, germline CDH1 mutations have not been described in patients with LBC in non-HDGC families.
17660459
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
Cleft lip/palate and CDH1 /E-cadherin mutations in families with hereditary diffuse gastric cancer .
15831593
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
Direct evidence of E-cadherin mutations triggering tumorigenesis has come from the finding of inactivating germline mutations of the gene (CDH1 ) in hereditary diffuse gastric cancer (HDGC ).
12588804
2003
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
Direct evidence of E-cadherin mutations triggering tumorigenesis has come from the finding of inactivating germline mutations of the gene (CDH1 ) in hereditary diffuse gastric cancer (HDGC ).
12588804
2003
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells.
14500541
2003
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
UNIPROT
E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer.
12216071
2002
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
GeneticVariation
UNIPROT
We screened five Korean familial gastric cancer patients to investigate germline mutations of the E-cadherin gene.
10319582
1999
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
10072428
1999
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
10072428
1999
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
A causal role for E-cadherin in the transition from adenoma to carcinoma.
9515965
1998
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CTD_human
E-cadherin germline mutations in familial gastric cancer.
9537325
1998
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
E-cadherin germline mutations in familial gastric cancer.
9537325
1998
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion.
8236461
1993
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
Expression of E- and P-cadherin in gastric carcinomas.
2009537
1991
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
CLINGEN
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role.
2070412
1991
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hereditary Diffuse Gastric Cancer
0.800
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
3557
Gene Symbol:
IL1RN
IL1RN
Hereditary Diffuse Gastric Cancer
0.500
Biomarker
CTD_human
×
Entrez Id:
3557
Gene Symbol:
IL1RN
IL1RN
Hereditary Diffuse Gastric Cancer
0.500
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Hereditary Diffuse Gastric Cancer
0.400
Biomarker
CTD_human
Point mutations of K-ras and H-ras genes in forestomach neoplasms from control B6C3F1 mice and following exposure to 1,3-butadiene, isoprene or chloroprene for up to 2-years.
11397402
2001
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Hereditary Diffuse Gastric Cancer
0.400
Biomarker
CTD_human
DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene.
10874023
2000