Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 AlteredExpression BEFREE Combined overexpression of miR-520g and miR-520h inhibited bortezomib-resistant MM tumor growth <i>in vivo</i>. 31204563

2019

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 AlteredExpression BEFREE Ectopic expression of miR-520g conferred resistance to 5-fluorouracil (5-FU)- or oxaliplatin-induced apoptosis in vitro and reduced the effectiveness of 5-FU in the inhibition of tumor growth in a mouse xenograft model in vivo. 25616665

2015

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 AlteredExpression BEFREE Here, we observed elevated miR-520g expression in tumor samples from HCC patients with relapse and metastasis, and this high miR-520g expression was correlated with poor survival. 25436421

2015

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 Biomarker BEFREE Elevated microRNA-520g in pre-eclampsia inhibits migration and invasion of trophoblasts. 28292471

2017

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 AlteredExpression BEFREE Dysregulated miR-520g expression is involved in these processes in hepatic and colorectal cancers. 27049921

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 AlteredExpression BEFREE Highly expressed mir-520g is associated with lymph node metastasis and low differentiation of breast cancer, and also is associated with mammary gland invasion in breast cancer. 26957267

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 Biomarker BEFREE These findings indicate that the p53/miR-520g/p21 signaling axis plays an important role in the response of colorectal cancer to chemotherapy. 25616665

2015

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.010 AlteredExpression BEFREE Combined overexpression of miR-520g and miR-520h inhibited bortezomib-resistant MM tumor growth <i>in vivo</i>. 31204563

2019

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
0.010 Biomarker BEFREE Tissue Factor Regulation by miR-520g in Primitive Neuronal Brain Tumor Cells: A Possible Link between Oncomirs and the Vascular Tumor Microenvironment. 26687818

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 Biomarker BEFREE We also explored the relationship between mir-520g and several prognostic factors in breast cancer patients. 26957267

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0025149
Disease: Medulloblastoma
Medulloblastoma
0.010 AlteredExpression BEFREE In medulloblastoma cell lines (DAOY and UW228) engineered to express miR-520g, a biologically active constituent of the C19MC cluster, we observed reduced TF expression, procoagulant and TF signaling activities (responses to factor VIIa stimulation), and diminished TF emission as cargo of extracellular vesicles. 26687818

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0027668
Disease: Neoplasms, Vascular Tissue
Neoplasms, Vascular Tissue
0.010 Biomarker BEFREE Tissue Factor Regulation by miR-520g in Primitive Neuronal Brain Tumor Cells: A Possible Link between Oncomirs and the Vascular Tumor Microenvironment. 26687818

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.010 Biomarker BEFREE This study suggests that miR-520g contributes to tumor progression and drug resistance by post-transcriptionally downregulating DAPK2, and that miR-520g may be a valuable therapeutic target in patients with EOC. 27049921

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma
0.010 AlteredExpression BEFREE In medulloblastoma cell lines (DAOY and UW228) engineered to express miR-520g, a biologically active constituent of the C19MC cluster, we observed reduced TF expression, procoagulant and TF signaling activities (responses to factor VIIa stimulation), and diminished TF emission as cargo of extracellular vesicles. 26687818

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma
0.010 AlteredExpression BEFREE In medulloblastoma cell lines (DAOY and UW228) engineered to express miR-520g, a biologically active constituent of the C19MC cluster, we observed reduced TF expression, procoagulant and TF signaling activities (responses to factor VIIa stimulation), and diminished TF emission as cargo of extracellular vesicles. 26687818

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer
0.010 Biomarker BEFREE This study suggests that miR-520g contributes to tumor progression and drug resistance by post-transcriptionally downregulating DAPK2, and that miR-520g may be a valuable therapeutic target in patients with EOC. 27049921

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.010 Biomarker BEFREE We also explored the relationship between mir-520g and several prognostic factors in breast cancer patients. 26957267

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
Secondary malignant neoplasm of lymph node
0.010 AlteredExpression BEFREE Highly expressed mir-520g is associated with lymph node metastasis and low differentiation of breast cancer, and also is associated with mammary gland invasion in breast cancer. 26957267

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial
0.010 Biomarker BEFREE This study suggests that miR-520g contributes to tumor progression and drug resistance by post-transcriptionally downregulating DAPK2, and that miR-520g may be a valuable therapeutic target in patients with EOC. 27049921

2016

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 AlteredExpression BEFREE Here, we observed elevated miR-520g expression in tumor samples from HCC patients with relapse and metastasis, and this high miR-520g expression was correlated with poor survival. 25436421

2015

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.010 AlteredExpression BEFREE Accordingly, we conclude that high miR-520g expression promotes HCC cell mobility and EMT by targeting SMAD7, and this is correlated with reduced survival in HCC patients. 25436421

2015

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
Malignant neoplasm of colon and/or rectum
0.010 Biomarker BEFREE These findings indicate that the p53/miR-520g/p21 signaling axis plays an important role in the response of colorectal cancer to chemotherapy. 25616665

2015

Entrez Id: 574484
Gene Symbol: MIR520G
MIR520G
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.010 GeneticVariation BEFREE The C allele of SNP rs7201 increases a risk for endometriosis because of out of regulation by microRNA-520g. 23364396

2013