Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.600 Biomarker BEFREE Our observed genetic interaction between PGF and VEGFA appears relevant to psoriasis, a disease with an angiogenic basis, and may influence development of an antiangiogenic approach to treatment. 31545526

2020

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.600 Biomarker BEFREE Due to the effect of inhibiting production of VEGF, acitretin can effectively treat psoriasis. 31148871

2020

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.600 GeneticVariation BEFREE Haplotype analysis suggests that the coexistence of the polymorphisms rs1799964 (TNF-α), rs2010963 (VEGF), rs833061 (VEGF), and rs6311 (5HT2A) may be a protective factor for psoriasis. 31148856

2020

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF. 30639585

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE Serum vascular endothelial growth factor (VEGF) concentrations in colon cancer patients of the two groups were evaluated before and after chemotherapy. 31127996

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 AlteredExpression BEFREE This study aimed to evaluate the prognostic value of MVD in stage II and III colon cancer and its relation to tumour-stroma-percentage (TSP) and expression of HIF1A and VEGFA. 31420015

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE Stimulation of colon cancer cells with VEGF-A and placental growth factor (PlGF) activated VEGF receptor-1 (VEGFR-1) and increased proliferation activity in an autocrine EGF/EGF receptor (EGF-R)-dependent manner. 31717527

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE Chemokine receptor 7 targets the vascular endothelial growth factor via the AKT/ERK pathway to regulate angiogenesis in colon cancer. 31348616

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.600 AlteredExpression BEFREE Topical application or subcutaneous injection of the Fib3 antibody decreased Psoriasis Area and Severity Index and VEGF expression in imiquimod-treated mice. 30146751

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.600 Biomarker BEFREE The objective of the study was to elucidate the mechanism by which siRNA-mediated silencing of KRT16 affects keratinocyte proliferation and vascular endothelial growth factor (VEGF) secretion in psoriasis through the extracellular signal-related kinase (ERK) signaling pathway. 30942529

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.600 Biomarker BEFREE Prolactin and the vascular endothelial growth factor seem to play a key role in psoriasis pathogenesis regarding hyperproliferation of epidermal keratinocytes and dermal vascular ectasia. 31384319

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion
0.600 Biomarker BEFREE The intravitreous injection of therapeutic proteins that neutralize vascular endothelial growth factor (VEGF) family members is efficient to reduce macular edema associated with wet age-related macular degeneration (AMD), retinal vein occlusion (RVO) and diabetic retinopathy (DR). 31173913

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion
0.600 Biomarker BEFREE IMPACT OF RETINAL ISCHEMIA ON FUNCTIONAL AND ANATOMICAL OUTCOMES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY IN PATIENTS WITH RETINAL VEIN OCCLUSION. 31157714

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion
0.600 Biomarker BEFREE Association of Disorganization of Retinal Inner Layers With Visual Acuity Response to Anti-Vascular Endothelial Growth Factor Therapy for Macular Edema Secondary to Retinal Vein Occlusion. 30286219

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion
0.600 Biomarker BEFREE The top cited references mainly presented anti-VEGF medications on the management of RVO. 31528507

2019

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE A gene signature comprising LAMA1, ITGB1, ITGA2, CXCR4 and VEGFA has negative predictive value in colon cancer. 29907957

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE The aim was to investigate the predictive value of postoperative VEGF serum concentration in patients undergoing surgery for colon cancer. 28683891

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE We have used 20 Male wistar rats for the formation of colon cancer model and utilized albumin as carrier molecule for the delivery of siRNA against vascular endothelial growth factor receptor 2 (VEGF R2). 29709588

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 AlteredExpression BEFREE We examined the effect of genipin on the intracellular level of HIF-1α and extracellular level of VEGF using the colon cancer cell line HCT116. 29630948

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 AlteredExpression BEFREE miR‑1 inhibits the progression of colon cancer by regulating the expression of vascular endothelial growth factor. 29845255

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE The rationale for this therapeutic approach is based on the fact that antiangiogenic drugs can make tumors hypoxic, and thus more sensitive to PIM inhibitors.<b>Experimental Design:</b> Xenograft and orthotopic models of prostate and colon cancer were used to assess the effect of PIM activation on the efficacy of VEGF-targeting agents. 29084916

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 AlteredExpression BEFREE We evaluated the efficacy of bevacizumab-based anti-angiogenesis in combination with PDT as well as the resulting VEGF levels and microvessel density (MVD) in a mouse model of human colon cancer. 29894822

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE ALA PDT used in sublethal doses decreases release of VEGF in more aggressively growing SW620 colon cancer cell line in hypoxia-like conditions. 29079348

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.600 Biomarker BEFREE We evaluated the influence of 28 single-nucleotide polymorphisms in 12 genes in the VEGF pathway on the prognosis of 347 patients with stage II-III colon cancer. 29282362

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.600 Biomarker BEFREE In non-erythrodermic PF, VEGF positivity was similar to HI (P = 0.247), and lower than psoriasis (P = 0.049) and PV (P = 0.049). 29489039

2018