Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0000846
Disease: Agenesis
Agenesis
0.030 Biomarker BEFREE To date, the mutation spectra of non-syndromic form of familial and sporadic tooth agenesis in humans have revealed defects in various such genes that encode transcription factors, MSX1 and PAX9 or genes that code for a protein involved in canonical Wnt signaling (AXIN2), and a transmembrane receptor of fibroblast growth factors (FGFR1). 24121910

2014

Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0000846
Disease: Agenesis
Agenesis
0.030 Biomarker BEFREE Also it appears that preferential premolar agenesis is associated with FGFR1 (P = 0.014) and IRF6 (P = 0.002) markers. 17318851

2007

Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0000846
Disease: Agenesis
Agenesis
0.030 GeneticVariation BEFREE IHH associated with impaired olfactory function (Kallmann syndrome) may be caused by mutations of the X-chromosomal KAL1 (encoding anosmin) or the fibroblast growth factor receptor 1 genes (FGFR1), both leading to agenesis of olfactory and GnRH-secreting neurons. 15722618

2005