Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium 		0.340 Biomarker BEFREE Genomic analysis showed that most tumors spontaneously acquired <i>Trp53</i> mutations, pointing to a triad of pathways (p53, PI3K, and Fbxw7) as the critical combination underpinning uterine carcinosarcoma, and to Fbxw7 as a key driver of this enigmatic endometrial cancer type. 31772025

2019
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium 		0.340 GeneticVariation BEFREE In vitro effects of FBXW7 mutation in serous endometrial cancer: Increased levels of potentially druggable proteins and sensitivity to SI-2 and dinaciclib. 29963728

2018
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium 		0.340 GeneticVariation BEFREE Here we show that hCDC4 gene mutation and hyperphosphorylation of cyclin E, a parameter that usually correlates with hCDC4 mutation, have a strong statistically significant association with polypoidy and aneuploidy in endometrial cancer. 15048079

2004
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium 		0.340 GeneticVariation BEFREE hCDC4 gene mutations in endometrial cancer. 12183400

2002
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium 		0.340 CausalMutation CGI