×
Entrez Id:
53347
Gene Symbol:
UBASH3A
UBASH3A
Cholangitis, Sclerosing
0.400
Biomarker
CTD_human
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017
×
Entrez Id:
53347
Gene Symbol:
UBASH3A
UBASH3A
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017
×
Entrez Id:
53347
Gene Symbol:
UBASH3A
UBASH3A
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
4843
Gene Symbol:
NOS2
NOS2
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.
23603763
2013
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
Biomarker
CTD_human
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
21151127
2011
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
21151127
2011
×
Entrez Id:
4843
Gene Symbol:
NOS2
NOS2
Cholangitis, Sclerosing
0.400
Biomarker
CTD_human
Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes.
12612912
2003
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
GeneticVariation
BEFREE
To generalize these observations, we suppressed β-catenin in Mdr2 knockout (KO) mice, which develop sclerosing cholangitis due to regurgitation of BA from leaky ducts.
31489648
2019
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
Biomarker
CTD_human
Galunisertib modifies the liver fibrotic composition in the Abcb4Ko mouse model.
29808285
2018
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
Biomarker
BEFREE
Because MDR2 (rodent orthologue of human MDR3 ) knockout mice develop sclerosing cholangitis , it is attractive to speculate that MDR3 defects could also play an important role in cholangiopathies in humans.
17295178
2007
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
Biomarker
CTD_human
Multidrug resistance gene 2 knockout mice (Mdr2 (-/-)) represent a well-characterized model for sclerosing cholangitis .
16472600
2006
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
Cholangitis, Sclerosing
0.300
Biomarker
CTD_human
Consistent with a role for HIFs in liver fibrosis in cholestatic liver disease, nuclear HIF-1 α protein was present in macrophages, hepatocytes, and fibroblasts in the livers from patients with primary biliary cirrhosis and primary sclerosing cholangitis .
22271822
2012
×
Entrez Id:
10018
Gene Symbol:
BCL2L11
BCL2L11
Cholangitis, Sclerosing
0.300
Biomarker
CTD_human
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
21151127
2011
×
Entrez Id:
8209
Gene Symbol:
GATD3A
GATD3A
Cholangitis, Sclerosing
0.110
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
8209
Gene Symbol:
GATD3A
GATD3A
Cholangitis, Sclerosing
0.110
Biomarker
BEFREE
PDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury in rodents: possible implications for sclerosing cholangitis .
23207146
2013
HLA-DQB1
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
28779025
2018
×
Entrez Id:
30820
Gene Symbol:
KCNIP1
KCNIP1
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
28779025
2018
×
Entrez Id:
3431
Gene Symbol:
SP110
SP110
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
28779025
2018
LINC01967
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
28779025
2018
×
Entrez Id:
51164
Gene Symbol:
DCTN4
DCTN4
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
28779025
2018
×
Entrez Id:
11262
Gene Symbol:
SP140
SP140
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
28779025
2018
×
Entrez Id:
6311
Gene Symbol:
ATXN2
ATXN2
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017