Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia
0.310 AlteredExpression BEFREE Gene knockdown of PHLPP1 in NRK52E cells enhanced Nrf2-responsive antioxidant enzymes HO-1 and NQO-1 which suggested that PHLPP1 up-regulation during hyperglycemia lowers Nrf2 stability via GSK3β activation. 29655866

2018

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia
0.310 Therapeutic CTD_human NQO1 knockout (KO) mice showed hyperglycemia, body weight loss, impaired glucose clearance rate and a lower plasma insulin level after MLDS treatment. 23458895

2013