Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 Biomarker BEFREE Chromosomal Instability and mTORC1 Activation through PTEN Loss Contribute to Proteotoxic Stress in Ovarian Carcinoma. 31530568

2019

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 Biomarker BEFREE To explore the role of miR-200a combined with PTEN in the progression of ovarian carcinoma. 30024595

2018

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 Biomarker BEFREE Conditional homozygous knockout of PTEN mediated by PAX8-cre recombinase was sufficient to drive endometrioid and serous borderline ovarian carcinoma, providing the first model of FTE-derived borderline tumors. 29367766

2018

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 AlteredExpression BEFREE The function of miR-222 was detected in ovarian carcinoma to verify the regulation of phosphatase and tensin homolog (PTEN) by miR-222. miR-222 expression in ovarian carcinoma tissues and cell lines were examined using RT-qPCR. 29963173

2018

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 Biomarker BEFREE Although many tumors presented a single lesion (28/93, of which 23 overexpressed PIK3CA, 1 overexpressed AKT and 4 had lost PTEN), many OC (35/93) presented multiple alterations within the PI3K pathway. 23408974

2013

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 GeneticVariation BEFREE In these cases, there is a high frequency of atypia in the endometriosis, and the endometriosis and the associated ovarian carcinoma may show identical PTEN mutations. 15381900

2004

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 GenomicAlterations CGI

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 Biomarker HPO

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.460 CausalMutation CGI