Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 11277
Gene Symbol: TREX1
TREX1
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.420 GeneticVariation BEFREE The RVCL disorders characterized by profound retinopathy are associated with mutations in TREX1, which encodes an abundant 3'-5' DNA-specific exonuclease. 21062344

2011
Entrez Id: 11277
Gene Symbol: TREX1
TREX1
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.420 Biomarker GENOMICS_ENGLAND Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus. 16845398

2006
Entrez Id: 11277
Gene Symbol: TREX1
TREX1
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.420 GeneticVariation BEFREE The main hereditary vascular conditions involving both retinal and cerebral vessels include cerebroretinal vasculopathy, HERNS (hereditary endotheliopathy with retinopathy, nephropathy, and stroke), and hereditary vascular retinopathy; all are linked to the same locus on chromosome 3p21. 12525718

2003
Entrez Id: 11277
Gene Symbol: TREX1
TREX1
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.420 Biomarker HPO