Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE The Xpert platform gave positive results for TB for 11 samples with negative results on the MGIT320 platform. 31596198

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE Compared to culture and/or Xpert MTB/RIF positive TB, the sensitivity and specificity (95% CI) for the criteria were 37 (20-58) and 84 (79-87)%; and 22 (9-43) and 83 (79-87)%, respectively. 31632942

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE The current ICF algorithm detected ≥98% of all TB cases in both subgroups but required ≥85% of all patients to undergo Xpert testing. 31658185

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE Implementation of GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit® increased tuberculosis diagnostic algorithms sensitivity from 73.6% (95% CI 67.1-79.3%) up to 88.1% (95% CI 82.8-91.9%). 31221109

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE Swabs were tested from South African adult subjects, including sputum GeneXpert MTB/RIF (GeneXpert)-confirmed TB patients (<i>n</i> = 138), sputum GeneXpert-negative but culture-positive TB patients (<i>n</i> = 10), ill non-TB patients (<i>n</i> = 37), and QuantiFERON-negative controls (<i>n</i> = 34). 30541931

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE In conclusion, our data demonstrate that the HAIN test is an accurate rapid test for detecting both RIF and INH resistance in TB patients. 31814743

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE We assessed the costs and operation dynamics of outreach and promotion efforts for up front Xpert MTB/RIF (Xpert) testing for pediatric presumptive tuberculosis (TB) patients in four major Indian cities. 30933997

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE Ability of Xpert MTB/RIF assay for rapid and simultaneous detection of MTB and RIF resistance in comparison with culture makes it a useful diagnostic tool in skeletal TB. 30880713

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE We evaluated the diagnostic performance of Ultra and Xpert for pulmonary TB diagnosis in a low-TB-burden setting. 30541937

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE LAM, in conjunction with sputum smear microscopy or Xpert MTB/RIF (Xpert) as compared to Mycobacterium tuberculosis culture, which was used as a reference standard.TB prevalence was 24.6%. 31550246

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 GeneticVariation BEFREE Smear-negative sputum, pleural fluid and cerebrospinal fluid (CSF) were collected from TB suspects at Beijing Chest Hospital (Beijing, China) and were examined using smear, Xpert and culture. 30796951

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE <b>Background:</b> Xpert MTB/RIF (Xpert) and culture are the most reliable methods for tuberculosis diagnosis but are still poorly accessible in many low resource countries. 31619525

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE Compared against centralized Xpert testing, decentralization was most favorable when testing volume at decentralized facilities and pre-treatment LTFU were high, and specimen transport network was exclusively established for TB. 31382959

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE HIV-infected children with suspected tuberculosis enrolled in Burkina Faso, Cambodia, Cameroon, and Vietnam (ANRS 12229 PAANTHER 01 Study), underwent clinical assessment, chest radiography, Quantiferon Gold In-Tube (QFT), abdominal ultrasonography, and sample collection for microbiology, including Xpert MTB/RIF (Xpert). 31455612

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE The studies published so far reported an increased sensitivity of Ultra when compared to Xpert, which represents a benefit for tuberculosis diagnosis. 30928564

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 GeneticVariation BEFREE The aim of this study was to determine the levels and patterns of resistance of MTB isolates to two key anti-TB drugs (rifampicin, RIF and isoniazid, INH) and the type of mutations in drug resistance genes (rpoB, katG and inhA) of the isolates at the southern coastal region of Andhra Pradesh, India, using commercially available GenoType MTBDRplus assay under the Revised National TB Control Program. 31421108

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 GeneticVariation BEFREE The Xpert® MTB/RIF assay (Cepheid, Sunnyvale, CA, USA) has been in routine use in Odessa Oblast, a region with the highest tuberculosis (TB) incidence in Ukraine, since 2013. 30590114

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE The median time from Xpert diagnosis to RR-TB treatment initiation was 12 days (interquartile range 3-60.2). 30759187

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE We performed a systematic review and meta-analysis to assess the accuracy of Abbott-RT and Abbott-RIF/INH for the detection of TB and DR-TB. 30902741

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 GeneticVariation BEFREE Seven major TB drugs (rifampin [RIF], isoniazid [INH], linezolid [LZD], moxifloxacin [MFX], clofazimine [CFZ], pyrazinamide [PZA], and kanamycin [KAN]) were quantified. 30939136

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE With the current availability of point-of-care nucleic acid amplification platforms (eg, Xpert Edge), these data inform much needed investment and resource allocation strategies in tuberculosis endemic settings. 31097281

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 GeneticVariation BEFREE Effect of two alternative methods of pooling sputum prior to testing for tuberculosis with genexpert MTB/RIF. 31029099

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE The Deeplex-MycTB-validated LODs ranged from 20% to 80% for XpertMTB/RIF, 20% to 70% for Xpert Ultra, 5% to 10% for GenoTypeMTBDRplusv2.0, and 1% to 10% for GenoscholarNTM+MDRTBII for the different mutations. 31413081

2019

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE Cost Analysis of Tuberculosis Diagnosis in Cambodia with and without Xpert<sup>®</sup> MTB/RIF for People Living with HIV/AIDS and People with Presumptive Multidrug-resistant Tuberculosis. 29862440

2018

Entrez Id: 54509
Gene Symbol: RHOF
RHOF
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.100 Biomarker BEFREE Xpert MTB/RIF (Xpert) is the preferred first-line test for all persons with tuberculosis (TB) symptoms in South Africa in line with a diagnostic algorithm. 29208074

2018