DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Adenocarcinoma of lung (disorder) ×

Gene: APC ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0152013
Disease:	Adenocarcinoma of lung (disorder)

Adenocarcinoma of lung (disorder)

0.410

AlteredExpression

BEFREE

Indeed, an APC/C gene expression signature is significantly associated with CFI-402257 response in breast and lung adenocarcinoma cell line panels.

29378962

2018

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0152013
Disease:	Adenocarcinoma of lung (disorder)

Adenocarcinoma of lung (disorder)

0.410

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0152013
Disease:	Adenocarcinoma of lung (disorder)

Adenocarcinoma of lung (disorder)

0.410

GeneticVariation

CLINVAR

Somatic mutations affect key pathways in lung adenocarcinoma.

18948947

2008

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0152013
Disease:	Adenocarcinoma of lung (disorder)

Adenocarcinoma of lung (disorder)

0.410

CausalMutation

CGI