Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE The present study provides that OP-1 may be promising in retarding disc degeneration in DM patients. 30872412

2019
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE This study provides that OP-1 may be efficacy in retarding mechanical overloading-exacerbated disc degeneration. 29440560

2018
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE The present study indicates that OP-1 may be helpful to inhibit inflammation-mediated disc degeneration. 30341245

2018
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE The present study sheds a new light on the protective role of OP-1 in regulating disc cell biology and provides some theoretical basis for the application of OP-1 in retarding/regenerating disc degeneration. 30459239

2018
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE This study provides that OP-1 may be efficacy in retarding inflammation-exacerbated disc degeneration. 29367112

2018
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE BMP-7/OP-1 has been shown to retard disc degeneration. 28102712

2017
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE Human bone morphogenetic protein 7 transfected nucleus pulposus cells delay the degeneration of intervertebral disc in dogs. 26218641

2017
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 AlteredExpression BEFREE In vivo analysis in a rabbit model of disc degeneration showed that implantation of BMSCs over-expressing BMP7 promoted cell differentiation and proliferation in the NP, as well as their own survival, and these effects were mediated by the Smad pathway. 26929154

2016
Entrez Id: 655
Gene Symbol: BMP7
BMP7
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.090 Biomarker BEFREE Combination therapy using BMP-7 and FoxC2 may be beneficial to the treatment of intervertebral disc degeneration. 26824865

2016