Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.330 Biomarker BEFREE 7-9-month old wild-type and secreted protein acidic and rich in cysteine (SPARC)-null (a model of disc degeneration and LBP) male mice were treated with TAK-242 (TLR4 inhibitor) once, and following a 10-day washout, mice were treated 3 times/week for 8 weeks. 29908959

2018
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.330 GeneticVariation BEFREE Inactivation of the SPARC gene in mice results in premature intervertebral disc degeneration. 20714283

2011
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.330 PosttranslationalModification BEFREE In parallel, we show that human subjects with back pain exhibit signs of disc degeneration and increased methylation of the SPARC promoter. 21867537

2011
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		0.330 Biomarker CTD_human Inactivation of the SPARC gene in mice results in premature intervertebral disc degeneration. 20714283

2011