Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease
0.060 GeneticVariation BEFREE Based on our results, VDR and its gene variants are highly associated with specific degenerative LDD endophenotypes. 31768839

2020

Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease
0.060 AlteredExpression BEFREE Plasma VDR levels and VDR expression were significantly lower in patients with LDD compared with controls (all P < 0.05). 31127184

2019

Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease
0.060 GeneticVariation BEFREE The VDR AA homozygous genotype was seen in 30(16.7%) patients with LDD and 20(8.7%) controls (codominant model: OR = 2.48; 95% CI 1.30-4.73, P = .005) with an estimated approximately 2.5-fold risk of developing LDD in individuals with this genotype. 29316495

2018

Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease
0.060 GeneticVariation BEFREE There was no evidence that the VDR gene polymorphisms (TaqI, FokI, ApaI) had significant associations with LDD risk. 27613009

2017

Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease
0.060 Biomarker BEFREE LDD is closely associated in occurrence and severity with occupational, environmental risk factors and susceptibility genes namely MMP-3, and VDR (ApaI). 23975061

2014

Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease
0.060 GeneticVariation BEFREE We investigated the association between vitamin-D receptor gene and estrogen receptor gene polymorphisms and lumbar disc disease in young adults. 12429765

2002