Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.350 Biomarker BEFREE In summary, ALK fusion-positive thyroid carcinomas are typically infiltrative PTC with common follicular growth, which may show tumor dedifferentiation associated with increased mortality. 31539879

2019
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.350 Biomarker BEFREE Mutations of the BRAF and RAS genes and rearrangement of the RET/PTC1, NTRK1, and ALK genes using 769 preoperative fine-needle aspiration specimens and resected PTCs were analyzed. 28293988

2017
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.350 GeneticVariation BEFREE No ALK translocations were identified in 36 PTCs with distant metastases, 28 poorly differentiated (insular) carcinomas, and 20 anaplastic carcinomas. 25501013

2015
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.350 FusionGene ORPHANET No ALK translocations were identified in 36 PTCs with distant metastases, 28 poorly differentiated (insular) carcinomas, and 20 anaplastic carcinomas. 25501013

2015
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.350 Biomarker BEFREE These findings could pave the way for the development of new targeted therapeutic strategies in the treatment of papillary thyroid carcinomas and point to ALK inhibitors as promising agents that merit rapid evaluation. 24475247

2014
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.350 FusionGene ORPHANET Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma. 25148236

2014
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.350 Biomarker BEFREE We found rearranged ALK in 10 of 19 radiation-exposed PTC cases, but none among 6 patients with PTC with no radiation exposure. 23050789

2012