Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4049
Gene Symbol: LTA
LTA
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.140 GeneticVariation GWASCAT Defining the genetic susceptibility to cervical neoplasia-A genome-wide association study. 28806749

2017
Entrez Id: 4049
Gene Symbol: LTA
LTA
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.140 Biomarker BEFREE There might be an association of the TLR2 and TLR4 pathways with the immunological response of TNF-α and TNF-β in cervical cancer. 28009429

2017
Entrez Id: 4049
Gene Symbol: LTA
LTA
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.140 GeneticVariation BEFREE The rare allele (A) of SNP rs2239704 in the 5' UTR of the LTA gene was significantly associated with increased risks of cervical cancer (OR=1.31, 95% CI: 1.15-1.50; adjusted p-value: 0.013) and vulvar cancer (OR=1.51, 95% CI: 1.30-1.75; adjusted p-value: 1.9 × 10(-5) ). 23824834

2014
Entrez Id: 4049
Gene Symbol: LTA
LTA
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.140 GeneticVariation BEFREE A significant association of CxCa with various polymorphisms was observed: rs1800797 in the IL-6 gene (odds ratio [OR] = 0.88, 95% confidence intervals [CI]: 0.79-0.99); rs1041981 in the LTA gene (OR = 0.87, 95% CI: 0.78-0.98), and rs9344 in the CCND1 gene (OR = 1.14, 95% CI: 1.02-1.27), for those individuals carrying the rare allele. 19585495

2009
Entrez Id: 4049
Gene Symbol: LTA
LTA
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.140 GeneticVariation BEFREE Lymphotoxin-alpha polymorphism and the risk of cervical cancer in Japanese subjects. 15639341

2005