Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 GeneticVariation BEFREE The haptoglobin (Hp) genotype is associated with type 2 diabetes related complications including increased risk for cerebrovascular pathology and worse cognitive performance. 30809196

2019

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 GeneticVariation BEFREE We review the diverse Hp genotypes, phenotypes and the impact on diabetes complications, including lessons from animal models and in vitro models. 29799294

2018

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 GeneticVariation BEFREE Haptoglobin (Hp) genotype 2-2 increases cardiovascular diabetes complications. 26002590

2016

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 GeneticVariation BEFREE The Haptoglobin (HP) 2-2 genotype increases cardiovascular diabetes complication incidence. 26684170

2016

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 GeneticVariation BEFREE Neuroimaging was completed in 94 participants of the Pittsburgh Epidemiology of Diabetes Complications study with Hp genotyping available (mean age, 49; duration, 41 years). 25213335

2015

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 Biomarker BEFREE Participants from the Epidemiology of Diabetes Complications study without prevalent stroke and Hp available were evaluated (n = 607; mean age 27.6 years and duration 19.3 years). 24994788

2014

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 GeneticVariation BEFREE Haptoglobin (Hp) genotype (Hp 1-1, 1-2, or 2-2) is associated with risk for type 2 diabetes complications, but its relationship with cognitive compromise, a growing concern in type 2 diabetes, has rarely been studied. 23990521

2013

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus
0.370 Biomarker CTD_human Divergent effects of alpha-tocopherol and vitamin C on the generation of dysfunctional HDL associated with diabetes and the Hp 2-2 genotype. 19769483

2010