Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 AlteredExpression BEFREE In this study, the evaluation of E-cadherin expression in an OC tissue microarray revealed its prognostic value to discriminate between advanced- and early-stage tumors, as well as serous tumors from other histologies. 28934230

2017

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 AlteredExpression BEFREE Decreased epithelial cadherin (E-cadherin) expression is hypothesized to be related to poor prognosis of ovarian cancer, but the predictive value is still inconsistent. 29113377

2017

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 Biomarker BEFREE The prognostic role of epithelial cadherin (E-cadherin) downregulation in ovarian cancer has been assessed for years while the results remain inconclusive. 29113366

2017

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 PosttranslationalModification BEFREE The findings showed that CDH1 promoter methylation had an increased risk of ovarian cancer in cancer tissues (OR = 8.71, P < 0.001) in comparison with nonmalignant tissues. 27067410

2016

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 Biomarker BEFREE PITX2-induced TGF-β pathway regulated the expression of invasion-associated genes, SNAI1, CDH1 and MMP9 (p < 0.01) that accounted for enhanced motility/invasion of ovarian cancers. 26298390

2015

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 PosttranslationalModification BEFREE In conclusion, Dysfunction of the cell cycle and/or the cell-cell adhesion molecule plays a role in the pathogenesis of ovarian cancer and that the analysis of the methylation of p15 and E-cadherin genes can provide clinically important evidence on which to base the treatment. 23572389

2015

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 Biomarker BEFREE These findings suggest that the expression of epithelial-mesenchymal transition-related genes such as ZEB2 and CDH1 may play important roles in the invasion process of advanced stage serous ovarian cancer. 19486012

2009

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 AlteredExpression BEFREE E-cadherin protein expression in was lower in C/C genotype carriers than T allele carriers in ovarian cancer tissue (P=0.02). 18035404

2008

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 Biomarker BEFREE Promoter CpG hypermethylation may be an alternative to mutation(s) to inactivate tumour suppressor genes such as MGMT, CDH1, RAR-beta and SYK, and this can also be an early event in the pathogenesis of OCs. 14970867

2004

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 Biomarker CTD_human Mutations of the E-cadherin gene in human gynecologic cancers. 8075649

1994

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 Biomarker GENOMICS_ENGLAND

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.690 GeneticVariation UNIPROT