Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 Biomarker CTD_human Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide. 19652463

2009

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 Biomarker CTD_human Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens. 17474063

2007

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 AlteredExpression LHGDN Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer. 17018607

2006

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 Biomarker CTD_human High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model. 15958052

2005

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 Biomarker BEFREE Possible enhancing effects of atrazine and nonylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats. 15132767

2004

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 AlteredExpression LHGDN Immunohistochemical analysis reveals a protective effect of H-ras expression mediated via apoptosis in node-negative breast cancer patients. 11788888

2002

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 Biomarker CTD_human Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice. 12165863

2002

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 PosttranslationalModification BEFREE Low-levels of increased methylation of HRAS (11p15) were observed between normal and tumor breast tissue samples from 8 patients. 8239493

1993

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 AlteredExpression BEFREE Steady state mRNA levels for transforming growth factor beta, erbB2, c-myc, and Ha-ras in the normal cells were greater than or comparable to those in all of the breast tumor lines. 3191480

1988