Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 Biomarker CTD_human Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. 23535731

2013
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 Biomarker BEFREE The levels of TRF2, TRF1, TIN2, and POT1 mRNA, but not telomerase reverse transcriptase (TERT) RNA, are inversely correlated with telomere content in breast tumors. 23342266

2012
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 GeneticVariation LHGDN A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women. 18413362

2008
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 AlteredExpression LHGDN Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc. 18586674

2008
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 Biomarker BEFREE Analysis of TERT in 103 primary breast tumors showed > 50% nuclei immunostaining in 58% of cases. 17656250

2007
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 GeneticVariation LHGDN Alteration of hTERT full-length variant expression level showed different gene expression profiles and genomic copy number changes in breast cancer. 16525654

2006
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 AlteredExpression BEFREE There was a strong correlation between detection of hTERT gene expression by ISH and of hTERT protein by ICH in tissue specimens from breast tumors. 16211220

2005
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 AlteredExpression LHGDN Quantitative and spatial measurements of telomerase reverse transcriptase expression within normal and malignant human breast tissues. 16179497

2005
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 Biomarker LHGDN Emerging role of p53, bcl-2 and telomerase activity in Egyptian breast cancer patients. 15545228

2004
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 Biomarker LHGDN In vitro quantification of the cytotoxic T lymphocyte response against human telomerase reverse transcriptase in breast cancer. 15202008

2004
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 AlteredExpression LHGDN BRCA1 inhibition of telomerase activity in cultured cells. 14612409

2003
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 AlteredExpression LHGDN Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome. 11788906

2002
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 AlteredExpression LHGDN A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer. 11916966

2002
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 Biomarker BEFREE Transcription and alternative splicing of telomerase reverse transcriptase in benign and malignant breast tumours and in adjacent mammary glandular tissues: implications for telomerase activity. 12210061

2002
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 AlteredExpression LHGDN Telomerase activity in breast cancer in Western India (Gujarat). 11936586

2002
Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.500 Biomarker HPO