Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5444
Gene Symbol: PON1
PON1
Amyotrophic Lateral Sclerosis, Sporadic
0.350 GeneticVariation BEFREE The data from the present study suggest that these SNPs of the PON gene cluster do not contribute to the risk for developing SALS in a Chinese population. 22884547

2012

Entrez Id: 5444
Gene Symbol: PON1
PON1
Amyotrophic Lateral Sclerosis, Sporadic
0.350 GeneticVariation BEFREE Paraoxonase (PON) gene polymorphisms have been associated with susceptibility to sporadic amyotrophic lateral sclerosis (ALS). 20381198

2011

Entrez Id: 5444
Gene Symbol: PON1
PON1
Amyotrophic Lateral Sclerosis, Sporadic
0.350 GeneticVariation BEFREE The results did not show that the -A162G polymorphism of the PON1 gene is a risk factor of sALS in a Polish population; it may affect, however, bulbar onset of the disease. 20625960

2010

Entrez Id: 5444
Gene Symbol: PON1
PON1
Amyotrophic Lateral Sclerosis, Sporadic
0.350 Biomarker BEFREE Recent reports describe a genetic association between the PON genes and sporadic amyotrophic lateral sclerosis (ALS). 20582942

2010

Entrez Id: 5444
Gene Symbol: PON1
PON1
Amyotrophic Lateral Sclerosis, Sporadic
0.350 AlteredExpression BEFREE Overall, promoter haplotypes that decrease PON1 expression were associated with SALS, whereas haplotypes that increase expression were associated with controls. 17204329

2007

Entrez Id: 5444
Gene Symbol: PON1
PON1
Amyotrophic Lateral Sclerosis, Sporadic
0.350 Biomarker CTD_human A gene-environment study of the paraoxonase 1 gene and pesticides in amyotrophic lateral sclerosis. 17204329

2007