Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE The Association between Epidermal Growth Factor Receptor Single Nucleotide Polymorphisms and Radiochemotherapy Response in Cervical Cancer. 31254173

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Whole Lesion Histogram Analysis Derived From Morphological MRI Sequences Might be Able to Predict EGFR- and Her2-Expression in Cervical Cancer. 30318289

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Here, we reveal that EGFR correlates with reduced disease-free survival in cervical cancer patients with chemotherapy. 31772161

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 AlteredExpression BEFREE Metabolo-volumetric parameters of 18F-FDG-PET can predict expression of EGFR and HIF 1alpha in uterine cervical cancer. 30530968

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE The Papillomavirus E5 Gene Does Not Affect EGFR Transcription and Overall Survival in Cervical Cancer. 31696949

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Circ-ATP8A2 promotes cell proliferation and invasion as a ceRNA to target EGFR by sponging miR-433 in cervical cancer. 31029604

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Positive crosstalk between EGFR and the TF-PAR2 pathway mediates resistance to cisplatin and poor survival in cervical cancer. 30093972

2018

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Hence, the aim of this study was to explore the therapeutic efficacy and underlying mechanism of the sensitization to radiation or cisplatin of icotinib hydrochloride (IH), a high-selective EGFR tyrosine kinase inhibitor (TKI), in the Hela S3 human CC cell line. 29551903

2018

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 AlteredExpression BEFREE Cervical cancer is frequent in females.Epidermal growth factor receptor has a prominent expression in certain malignant tumors. 30338793

2018

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE In conclusion, this study provides a rationale to initiate a clinical trial for cervical cancer with adoptively transferred allogeneic NK cells, employing either UCB-NK or PBNK + CET for EGFR-expressing tumors. 27783105

2017

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 AlteredExpression BEFREE Radiotherapy modulates expression of EGFR, ERCC1 and p53 in cervical cancer. 29160417

2017

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE These results suggest that HB‑EGF is an important EGFR ligand in cervical cancer and that cervical cancer cells are the predominant source of HB‑EGF. 28498437

2017

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Aptamer Functionalized Cisplatin-Albumin Nanoparticles for Targeted Delivery to Epidermal Growth Factor Receptor Positive Cervical Cancer. 27301192

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 AlteredExpression BEFREE In this study, we found that C23 and EGFR were highly expressed in cervical cancer tissues, while C23 on the cell surface mainly expressed in CC tissues with lymph node metastasis, and was correlated to EGFR statistically. 26254615

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Epidermal growth factor receptor kinase substrate 8 promotes the metastasis of cervical cancer via the epithelial-mesenchymal transition. 27573546

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 AlteredExpression BEFREE This meta-analysis demonstrates that EGFR overexpression is closely associated with reduced survival in patients with cervical cancer. 27438047

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 GeneticVariation BEFREE In this study, the presence of EGFR mutations in cervical cancer and its correlation with HPV were identified. 26762413

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE These results showed that miR-133a suppresses cervical cancer growth in vitro and in vivo through targeting EGFR, suggesting that miR-133a can be a potential target for the treatment of cervical cancer. 26134491

2015

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 GeneticVariation BEFREE Here we demonstrate that PTEN destabilization is induced by EGFR- or oncogenic PI3K mutation-mediated AKT activation in cervical cancer. 26183061

2015

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 PosttranslationalModification BEFREE EGFR promoter methylation status and EGFR tyrosine kinase inhibitor-sensitive mutations in cervical cancer may be significant for clinical outcome prediction using anti-EGFR treatment. 25789535

2015

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker BEFREE Studies in cervical cancer indicate that E5 increases epidermal growth factor receptor (EGFR) recycling to the cell surface and enhances growth factor signal transduction. 25027574

2014

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 PosttranslationalModification BEFREE A novel assay detecting the EGFR promoter methylation status in cervical cancer tissue samples using a hybridization-fluorescence polarization (FP) technique was developed. 23628821

2013

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 GeneticVariation BEFREE We investigated the association of single nucleotide polymorphisms (SNPs) in the human epidermal growth factor receptor (ERBB) family with cervical cancer. 23927961

2013

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 AlteredExpression BEFREE Although epidermal growth factor receptor (EGFR) is highly expressed in breast and ovarian tumor tissues, its regulation by the exogenous source of its ligand EGF in human papillomavirus (HPV)-associated cervical cancer remains unclear. 21946890

2012

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.400 Biomarker CTD_human Phase II study of cisplatin plus cetuximab in advanced, recurrent, and previously treated cancers of the cervix and evaluation of epidermal growth factor receptor immunohistochemical expression: a Gynecologic Oncology Group study. 21329967

2011