Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker BEFREE In this report, we aimed to explore the roles of gene polymorphisms affecting x-ray repair cross complementing 1 (XRCC1), the tumor protein p53 (TP53), and fibroblast growth factor receptor 3 (FGFR3) in the context of susceptibility to cervical cancer. 30616520

2019

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker BEFREE The frequency of FGFR3-TACC3-fusion-positive cervical cancer is also 1.9% (2/103) in an independent cohort. 29358619

2018

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker BEFREE The research conducted in this article examines a frequently identified fusion protein between FGFR3 and transforming acidic coiled-coil containing protein 3 (TACC3), frequently identified in glioblastoma, lung cancer, bladder cancer, oral cancer, head and neck squamous cell carcinoma, gallbladder cancer, and cervical cancer. 26869289

2016

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker BEFREE Fibroblast growth factor receptor-3 (FGFR3) is a receptor tyrosine kinase implicated in the tumorigenesis of multiple malignancies, including bladder and other urothelial cancers, multiple myeloma, and cervical cancer. 22285006

2013

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 GeneticVariation UNIPROT Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. 10471491

1999

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker CTD_human

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE Subgroup analyses based on race system showed that HLA-DPB1⁎13:01 was significantly associated with an increased risk of cervical cancer in Asia (OR=1.834, 95%CI: 1.107-3.039, Pz=0.019). 30009173

2018

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE The liver kinase B1 (LKB1) gene is a tumor suppressor associated with the hereditary Peutz-Jeghers syndrome and frequently mutated in non-small cell lung cancer and in cervical cancer. 30222967

2018

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE However, the significance of LKB1 mutations in cervical cancer initiation and progress has not been examined. 27546620

2017

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE No association was detected between HLA-DPB1 alleles and cervical cancer risk in the Japanese population. 27193219

2016

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE We investigated whether polymorphisms in the HLA-DPB1 gene were associated with cervical cancer risk in a Taiwanese population. 26031576

2015

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE Our study provides the first systematic investigation of the association of genetic variants in the HLA-DP region with cervical cancer susceptibility and provides further insight into the contribution of polymorphisms in the HLA-DP region to risk of cervical cancer. 24743517

2014

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 Biomarker BEFREE Heightened and sustained receptor activation was demonstrated by LKB1-deficient A549 (lung) and HeLaS3 (cervical) cancer cell lines. 24285539

2014

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 AlteredExpression BEFREE Gene expression profiles of cervical cancer HeLa cells stably expressing LKB1 were analyzed by microarray. 24792998

2014

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 Biomarker BEFREE Mir-155 promotes cervical cancer cell proliferation through suppression of its target gene LKB1. 25155037

2014

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation GWASDB We additionally replicated an association between HLA-DPB1 and HLA-DPB2 (HLA-DPB1/2) at 6p21.32 and cervical cancer (rs4282438, Pcombined, stringently matched=4.52×10(-27), per-allele ORstringently matched=0.75). 23817570

2013

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE These findings indicate that HLA-DP rs3077 and rs9277535 were candidate susceptibility markers for cervical cancer in Chinese females. 23428460

2013

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 Biomarker CTD_human We additionally replicated an association between HLA-DPB1 and HLA-DPB2 (HLA-DPB1/2) at 6p21.32 and cervical cancer (rs4282438, Pcombined, stringently matched=4.52×10(-27), per-allele ORstringently matched=0.75). 23817570

2013

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 AlteredExpression BEFREE LKB1 expression and the integrity of LKB1-AMPK signaling were determined with immunoblot in 6 cervical cancer cell lines. 22735790

2012

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE The results illustrate the value of pathway-based analysis to mine genome-wide data, and point to the importance of the MHC region and specifically the HLA-DPB1 locus for susceptibility to cervical cancer. 21716314

2011

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE Mutations in the tumor suppressor gene LKB1 are important in hereditary Peutz-Jeghers syndrome, as well as in sporadic cancers including lung and cervical cancer. 21926085

2011

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 AlteredExpression BEFREE Thus, homozygous deletions affecting LKB1 in cervical cancers may generate multiple fusion transcripts involving LKB1, SBNO2, and c19orf26. 20193846

2010

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE Somatic LKB1 mutations promote cervical cancer progression. 19340305

2009

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 Biomarker BEFREE The LKB1 serine-threonine kinase is a tumor suppressor that is inactivated in a large number of sporadic human lung non-small cell carcinomas (NSCLCs) and cervical cancers. 19724060

2009

Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.500 GeneticVariation BEFREE D6S2766 and D6S2764, which are located near to the region containing the HLA-DPB genes, were negatively related with cervical cancer (OR for the D6S2766-195 allele carriers = 0.50), and positively related with cervical cancer (OR for the D6S2764-209 allele carriers = 2.44), respectively. 18712835

2008