Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 50616
Gene Symbol: IL22
IL22
Selective immunoglobulin A deficiency
0.020 Biomarker BEFREE <b>Results:</b> By evaluating T cell dependent cytokine driven pathways linked to IgA isotype induction we identified a defect involving an IL-21 driven STAT3 activation isolated to B cells in sIgAD individuals. 30936864

2019

Entrez Id: 50616
Gene Symbol: IL22
IL22
Selective immunoglobulin A deficiency
0.020 Biomarker BEFREE Whilst statistical analysis of ELISA results showed significant differences between patients and healthy controls, in our set of patients functional tests yielded no evidence for an involvement of autoantibodies against BAFF, APRIL, or IL-21 in the pathogenesis of CVID or sIgAD. 28651547

2017