Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Therefore, we recommend routinely performing ascites CEA analysis in colorectal cancer surgery. 31802190

2020

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Preoperative neutrophil-lymphocyte ratio and CEA is associated with poor prognosis in patients with synchronous colorectal cancer liver metastasis. 30941323

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Effects of vitamin D and omega-3 fatty acids co-supplementation on inflammatory biomarkers, tumor marker CEA, and nutritional status in patients with colorectal cancer: a study protocol for a double blind randomized controlled trial. 31815661

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Since carcinoembryonic antigen (CEA; CEACAM5) is abundantly overexpressed in colorectal cancer, it is a potential target for tPDT of colorectal cancer. 31828541

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Older age, male sex, African-American race, elevated CEA and not undergoing curative surgery were independent risk factors of cardiovascular mortality in patients with colorectal cancer. 30604158

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Overall, CEA remains a reliable predictor of recurrence and survival after curative surgery in patients with colorectal cancer. 30822523

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE All patients with colorectal cancer underwent a surveillance colonoscopy for recurrence; 97% had a carcinoembryonic antigen test. 30615587

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Impact of CEA-targeting Nanoparticles for Drug Delivery in Colorectal Cancer. 30670480

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE The higher serum CEA level than that of healthy individuals led to its clinical application as a diagnostic biomarker for colorectal cancer. 30905451

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Physiologically Based Modeling of the Pharmacokinetics of "Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibodies in Colorectal Cancer Xenograft Mouse Models. 30321546

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Applicability of postoperative carcinoembryonic antigen levels in determining post-liver-resection adjuvant chemotherapy regimens for colorectal cancer hepatic metastasis. 31689796

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE BACKGROUND Type 2 diabetes mellitus (T2DM) is related to the serum carcinoembryonic antigen (CEA) level, which is used as a marker of colorectal cancer. 31086125

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Carcinoembryonic antigen (CEA) is a commonly used biomarker in colorectal cancer. 31543685

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE This novel oversecretion of LAMB1 was validated in colorectal cancer patient serum samples, and ROC analyses showed that LAMB1 performed better than carcinoembryonic antigen (CEA) as a clinical diagnostic biomarker for colorectal cancer. 30980318

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE The clinical impact of monitoring serum p53 antibodies, carbohydrate antigen19-9, and carcinoembryonic antigen in patients with colorectal cancer has not been fully evaluated. 31820210

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Methylated Septin 9 and Carcinoembryonic Antigen for Serological Diagnosis and Monitoring of Patients with Colorectal Cancer After Surgery. 31316143

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE In vivo, a murine surrogate of HERA-CD40L-stimulated clonal expansion of OT-I-specific murine CD8 T cells and showed single agent antitumor activity in the CD40 syngeneic MC38-CEA mouse model of colorectal cancer, suggesting an involvement of the immune system in controlling tumor growth. 30273198

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE The aim of the study is to determine the value of elevated pre- and postoperative serum carcinoembryonic antigen levels (CEA > 5 µg/L) as an independent prognostic factor for locoregional and distant recurrence in patients who underwent curative surgery for colorectal cancer. 30852955

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Serum tumor markers, including CEA and CA19-9, have become the focus of research on colorectal cancer in recent years. 30854125

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE To test this hypothesis, we analyzed CEA and CA19-9 serum levels in patients with advanced colorectal cancer who received cetuximab in combination with chemotherapy. 30805037

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Carcinoembryonic antigen (CEACAM5, CEA) is a known tumor marker for colorectal cancer that localizes in a polarized manner to the apical surface in normal colon epithelial cells whereas in cancer cells it is present at both the apical and basolateral surfaces of the cells. 29304557

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE To examine overall mortality, colorectal cancer-specific mortality, and colorectal cancer-specific recurrence rates among patients with stage II or III colorectal cancer who were randomized after curative surgery to 2 alternative schedules for follow-up testing with computed tomography and carcinoembryonic antigen. 29800179

2018

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE A microfluidic paper analytical device (μPAD) was created for the sensitive quantification of cancer antigens, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9), from human whole blood and serum, toward diagnosis and prognosis of colorectal cancer. 28922620

2018

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Glycan analysis of colorectal cancer samples reveals stage-dependent changes in CEA glycosylation patterns. 29507546

2018

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Evaluation of Serum CEA, CA19-9, CA72-4, CA125 and Ferritin as Diagnostic Markers and Factors of Clinical Parameters for Colorectal Cancer. 29426902

2018