Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
CUI: C4725671
Disease: High-Risk Neuroblastoma
High-Risk Neuroblastoma
0.020 Biomarker BEFREE CFC1 inhibited Activin A-induced NB cell differentiation and Smad2 phosphorylation in NB cell lines, indicating its involvement in tumorigenesis related to EGF-CFC co-receptor family molecule pathways. 28620148

2017

Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
CUI: C4725671
Disease: High-Risk Neuroblastoma
High-Risk Neuroblastoma
0.020 Biomarker BEFREE Growing evidence suggests a major role for Src-homology-2-domain-containing phosphatase 2 (SHP2/PTPN11) in MYCN-driven high-risk neuroblastoma, although biologic confirmation and a plausible mechanism for this contribution are lacking. 28329685

2017