Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3916
Gene Symbol: LAMP1
LAMP1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 GeneticVariation BEFREE It is reported that oncogenic exosomes contain factors known to regulate the pre-metastatic niche (S100A4, F3, ITGβ5, ANXA1), clinically-relevant proteins which correlate with poor prognosis (CLDN1, MUC1) as well as protein networks involved in various cancer hallmarks including proliferation (CLU, CAV1), invasion (PODXL, ITGA3), metastasis (LAMP1, ST14) and immune surveillance escape (B2M). 30893511

2019

Entrez Id: 3916
Gene Symbol: LAMP1
LAMP1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 Biomarker BEFREE These findings suggest that UBL4A exerts an antitumor effect on autophagy-related proliferation and metastasis in PDAC by directly targeting LAMP1. 31288830

2019

Entrez Id: 3916
Gene Symbol: LAMP1
LAMP1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 Biomarker BEFREE To establish the role of cell surface LAMP1 in metastasis and to understand the possible mechanism by which it facilitates lung colonization, LAMP1 was downregulated in high metastatic B16F10 cells using shRNAs cloned in a doxycycline inducible vector. 24845565

2014

Entrez Id: 3916
Gene Symbol: LAMP1
LAMP1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 Biomarker BEFREE Because two other members of the LAMP family of lysosomal membrane glycoproteins, LAMP1 and LAMP2, were previously implicated in potentially modulating the interaction of vascular endothelial and cancer cells, we hypothesized that LAMP3 might also play an important part in metastasis. 16204031

2005

Entrez Id: 3916
Gene Symbol: LAMP1
LAMP1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 Biomarker BEFREE Molecular characterization of P2B/LAMP-1, a major protein target of a metastasis-associated oligosaccharide structure. 2676155

1989