Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64717
Gene Symbol: TRG-CCC2-2
TRG-CCC2-2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker BEFREE Response to CRT was determined based on Dworak tumour regression grade (TRG); tumours with complete (TRG 4) or near-complete (TRG 3) regression were grouped as good responders, and those with TRG 1 as non-responders. 31197828

2019

Entrez Id: 64717
Gene Symbol: TRG-CCC2-2
TRG-CCC2-2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 GeneticVariation BEFREE According to Rödel's pathological tumour regression grade (TRG), patients were considered non-responders (NR; TRG0-2), partial responders (PR; TRG3), and complete responders (CR; TRG4). 29459138

2018

Entrez Id: 64717
Gene Symbol: TRG-CCC2-2
TRG-CCC2-2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 GeneticVariation BEFREE In the subgroup analysis, elevated CRP was a significant prognostic factor in patients with node-positive disease (P = 0.025) and was associated with poorer tumor regression (TRG4-5; P = 0.011). 30288654

2018

Entrez Id: 64717
Gene Symbol: TRG-CCC2-2
TRG-CCC2-2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker BEFREE The values of pre-nCRT and post-nCRT IVIM-DWI parameters (ADC, D, D* and f), together with the percentage changes (∆% parametric value) induced by nCRT, were compared between the pCR (tumour regression grade [TRG] 4) and non-pCR (TRG 0, 1, 2 or 3) groups and between the GR (TRG 3 or 4) and PR (TRG 0, 1 or 2) groups based on the Dworak TRG system. 28819296

2017

Entrez Id: 64717
Gene Symbol: TRG-CCC2-2
TRG-CCC2-2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker BEFREE There was no difference between the chemotherapy plus surgery and surgery-alone group regarding overall and disease-free survival (p = 0.351 and p = 0.529).Pathological good response (i.e. tumor regression grading [TRG] 1-3) was achieved in 32 patients (34%), whereas 81 (66%) had poor response (TRG 4). 27424786

2017

Entrez Id: 64717
Gene Symbol: TRG-CCC2-2
TRG-CCC2-2
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker BEFREE The outcomes were measured by tumor regression grade (TRG) as a major response (TRG 1 and TRG 2) or as a poor response (TRG3, TRG4, and TRG5). 21167658

2012