Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 Biomarker BEFREE Intriguingly, the therapeutic studies in SKOV-3 human ovarian carcinoma and MDA-MB-231 human breast tumor xenografted in nude mice revealed that GrB-EGFR/CD44-NGs at a low dose of 3.85 nmol GrB equiv/kg induced nearly complete growth suppression of both tumors, which was obviously more effective than GrB-CD44-NGs, without causing any adverse effects. 28675028

2017

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 AlteredExpression BEFREE We show a high therapeutic potential for combinatorial treatment of ovarian carcinoma with a novel DDS that effectively transports siRNA targeting to CD44 mRNA simultaneously with cytotoxic agents. 24036854

2013

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 Biomarker BEFREE Hyaluronan oligomers-HPMA copolymer conjugates for targeting paclitaxel to CD44-overexpressing ovarian carcinoma. 22350800

2012

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.040 AlteredExpression BEFREE In order to test this postulate, the expression of three important CAMs involved in tumor processes (CD44, ICAM-1 and LFA-3) in the human cancer cell lines HT29 (colon adenocarcinoma), A431 (squamous epidermal carcinoma) and A2780 (ovarian carcinoma) grown in monolayer or as multicellular spheroids was compared. 10470114

1999